Factors Predicting Success in Lung Transplant Recipients Who Have Undergone Intensive Post-operative Rehabilitation

NCT ID: NCT03299504

Last Updated: 2018-08-24

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

105 participants

Study Classification

OBSERVATIONAL

Study Start Date

2017-09-26

Study Completion Date

2018-04-01

Brief Summary

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This is a retrospective review of the COLTT program outcomes and factors that predict recovery of functional status after lung transplantation.

Detailed Description

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The Center of Life for Thoracic Transplant (COLTT) program is a daily (5 days per week) intensive rehabilitation program for patients who have undergone lung transplant. Patients are enrolled in COLTT as part of standard care after hospital discharge. This study is a retrospective review of seventy patients that measures the efficacy of the COLTT program and establishes predictors of patient success.This study will also measure the effect of functional outcomes on hospital readmission post COLTT discharge.

Conditions

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Lung Transplant

Study Design

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Observational Model Type

COHORT

Study Time Perspective

RETROSPECTIVE

Interventions

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Exercise

5 days per week, 2.5 hours per day strength, balance and endurance training on an outpatient basis

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* All patients who completed the COLTT program from May, 2016 to July, 2017.

Exclusion Criteria

* Any COLTT patients who were not new lung transplant recipients.
Minimum Eligible Age

18 Years

Maximum Eligible Age

80 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Indiana University Health Methodist Hospital

OTHER

Sponsor Role lead

Responsible Party

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Christen DiPerna

Dedicated Physical Therapist

Responsibility Role PRINCIPAL_INVESTIGATOR

Locations

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IU Health Methodist Hospital

Indianapolis, Indiana, United States

Site Status

Countries

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United States

References

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Wickerson L, Rozenberg D, Janaudis-Ferreira T, Deliva R, Lo V, Beauchamp G, Helm D, Gottesman C, Mendes P, Vieira L, Herridge M, Singer LG, Mathur S. Physical rehabilitation for lung transplant candidates and recipients: An evidence-informed clinical approach. World J Transplant. 2016 Sep 24;6(3):517-31. doi: 10.5500/wjt.v6.i3.517.

Reference Type BACKGROUND
PMID: 27683630 (View on PubMed)

Langer D, Burtin C, Schepers L, Ivanova A, Verleden G, Decramer M, Troosters T, Gosselink R. Exercise training after lung transplantation improves participation in daily activity: a randomized controlled trial. Am J Transplant. 2012 Jun;12(6):1584-92. doi: 10.1111/j.1600-6143.2012.04000.x. Epub 2012 Mar 5.

Reference Type BACKGROUND
PMID: 22390625 (View on PubMed)

Walsh JR, Chambers DC, Davis RJ, Morris NR, Seale HE, Yerkovich ST, Hopkins PM. Impaired exercise capacity after lung transplantation is related to delayed recovery of muscle strength. Clin Transplant. 2013 Jul-Aug;27(4):E504-11. doi: 10.1111/ctr.12163. Epub 2013 Jul 2.

Reference Type BACKGROUND
PMID: 23815281 (View on PubMed)

Strassmann A, Steurer-Stey C, Lana KD, Zoller M, Turk AJ, Suter P, Puhan MA. Population-based reference values for the 1-min sit-to-stand test. Int J Public Health. 2013 Dec;58(6):949-53. doi: 10.1007/s00038-013-0504-z. Epub 2013 Aug 24.

Reference Type BACKGROUND
PMID: 23974352 (View on PubMed)

Springer BA, Marin R, Cyhan T, Roberts H, Gill NW. Normative values for the unipedal stance test with eyes open and closed. J Geriatr Phys Ther. 2007;30(1):8-15. doi: 10.1519/00139143-200704000-00003.

Reference Type BACKGROUND
PMID: 19839175 (View on PubMed)

Middleton A, Fritz SL, Lusardi M. Walking speed: the functional vital sign. J Aging Phys Act. 2015 Apr;23(2):314-22. doi: 10.1123/japa.2013-0236. Epub 2014 May 2.

Reference Type BACKGROUND
PMID: 24812254 (View on PubMed)

Dierich M, Tecklenburg A, Fuehner T, Tegtbur U, Welte T, Haverich A, Warnecke G, Gottlieb J. The influence of clinical course after lung transplantation on rehabilitation success. Transpl Int. 2013 Mar;26(3):322-30. doi: 10.1111/tri.12048. Epub 2013 Jan 7.

Reference Type BACKGROUND
PMID: 23294442 (View on PubMed)

Other Identifiers

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RCS1

Identifier Type: -

Identifier Source: org_study_id

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