Evaluation of Three Dimensional Echocardiography in Critical Care Medicine

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

Get a concise snapshot of the trial, including recruitment status, study phase, enrollment targets, and key timeline milestones.

Recruitment Status

TERMINATED

Total Enrollment

11 participants

Study Classification

OBSERVATIONAL

Study Start Date

2016-05-31

Study Completion Date

2019-08-31

Brief Summary

Review the sponsor-provided synopsis that highlights what the study is about and why it is being conducted.

Comparison of volumetric measurements obtained by three dimensional echocardiography with measurements obtained by thermodilution using a pulmonary artery catheter in the intensive care unit.

Related Clinical Trials

Explore similar clinical trials based on study characteristics and research focus.

Echocardiographic Evaluation in ARDS Patients

NCT03920189

Acute Respiratory Distress Syndrome Mechanical Ventilation Echocardiographic Ultrasound

COMPLETED

Echocardiography Guided Fluid Resuscitation in Critically Ill Patients.

NCT03296319

Fluid Responsiveness Echocardiography

COMPLETED NA

Evaluation of Acute Cardiogenic Dyspnoea With Thorax Echography and Pro-BNP in the Emergency Department

NCT02122640

Acute Heart Failure

COMPLETED

The Use of a Point-of-care Thoracic Ultrasound Protocol for Hospital Medical Emergency Teams

NCT03214809

Dyspnea Coma Hypotension and Shock

TERMINATED NA

Functional Hemodynamic Assessment in Shocked Patients in the Pediatric Intensive Care Unit

NCT06720493

Pediatric Shock

NOT_YET_RECRUITING

Detailed Description

Dive into the extended narrative that explains the scientific background, objectives, and procedures in greater depth.

Prospective, observational study evaluating three dimensional echocardiography for measuring hemodynamic variables versus the current gold standard (pulmonary artery catheter).

Critically ill patients with a severly compromised circulation due to a shock state with an advanced hemodynamic monitoring in place and the need for echocardiographic evaluation will be included.

While performing an echocardiography study stroke volume measurements using the bolus method for thermodilution will concomittantly be measured.

In case of insufficient image quality we are planning to use SonoVue echo contrast. Once the image quality has improved we will repeat the stroke volume measurements with the bolus thermodilution method while performing the echocardiography.

The acquired echocardiography loops will then be analysed and measured offline once deferred consent has been obtained. We will then compare the echocardiographic measurements with the measurement obtained by the pulmonary artery catheter (bolus method) - since this is the current reference method.

Conditions

See the medical conditions and disease areas that this research is targeting or investigating.

Shock

Study Design

Understand how the trial is structured, including allocation methods, masking strategies, primary purpose, and other design elements.

Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Study Groups

Review each arm or cohort in the study, along with the interventions and objectives associated with them.

ICU patient

Critically ill patients in our adult intensive care unit with the following characteristics:

* advanced hemodynamic monitoring in place including pulmonary artery catheter and arterial catheter
* intubated or tracheostomy in place
* echocardiography requested by the treating physician
* intervention of interest: hemodynamic assessment done by echocardiography and thermodilution (pulmonary artery catheter)

No interventions assigned to this group

Eligibility Criteria

Check the participation requirements, including inclusion and exclusion rules, age limits, and whether healthy volunteers are accepted.

Inclusion Criteria

* advanced hemodynamic monitoring with pulmonary artery catheter and arterial catheter in place
* patient intubated or tracheostomy in place
* clinical indication for performing an echocardiography
* ongoing sedation requirement

Exclusion Criteria

* Heart rhythm other than sinus rhythm or paced atrial rhythm
* Known allergy to sulphur-hexafluoride (SonoVue©)
* Artificial heart valves in place
* Any form of mechanical cardiac assist
* contraindication to performing a transesophageal echocardiography
* presence of significant cardiac valve regurgitation
* presence of an intracardiac shunt

Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No