Prognostic Value of CT dynamIc Myocardial Perfusion in Patients With Obstructive Coronary Artery Stenosis
NCT ID: NCT03250455
Last Updated: 2017-08-15
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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UNKNOWN
1748 participants
OBSERVATIONAL
2017-08-31
2020-12-31
Brief Summary
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Detailed Description
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Conditions
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Study Design
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COHORT
PROSPECTIVE
Study Groups
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CTA+CTP
CTA CTP
CT Angiography myocardial CT Perfusion
CTA only
CTA
CT Angiography
Interventions
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CTA CTP
CT Angiography myocardial CT Perfusion
CTA
CT Angiography
Eligibility Criteria
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Inclusion Criteria
2. stable chest pain with obstructive coronary stenosis (50-90%) assessed by CTA.
Exclusion Criteria
(2) Hemodynamically or clinically unstable condition systolic blood pressure (BP) \< 90 mmHg, atrial or ventricular arrhythmias, or persistent resting chest pain felt to be ischemic despite adequate therapy.
(3) Known CAD with prior Myocardial infarction (MI), percutaneous coronary intervention (PCI), coronary artery bypass graft (CABG).
(4) Known significant congenital, valvular (\> moderate) or cardiomyopathic process (hypertrophic cardiomyopathy or reduced systolic left ventricular function (LVEF) ≤ 40%)) which could explain cardiac symptoms.
(5) Contraindication to undergoing CTA, including but not limited to: a. Allergy to iodinated contrast agent, b. Unable to receive beta blockers, c. creatinine ≥1.7 mg/dl or GFR≤30 ml/min , d. Pregnancy.
(6) Contraindication to ATP, including but not limited to: a. II or III atrioventricular block, b. bronchial asthma, c. hypotension (SBP\<90mmHg), d. bronchial stenosis or bronchospasm, e. acute myocardial infarction, f. left main stenosis, g. unstable angina, h. allergy to aminophylline.
(7) Life expectancy \< 2 years. (8) Unable to provide written informed consent or participate in long-term follow-up.
18 Years
ALL
No
Sponsors
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Peking Union Medical College Hospital
OTHER
Shanghai Jiao Tong University Affiliated Sixth People's Hospital
OTHER
Guangdong Provincial People's Hospital
OTHER
Tianjin Medical University General Hospital
OTHER
Chinese Academy of Medical Sciences, Fuwai Hospital
OTHER
Responsible Party
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Bin Lu
chief of Radilogy
Principal Investigators
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Bin Lu, MD
Role: PRINCIPAL_INVESTIGATOR
Chinese Academy of Medical Sciences, Fuwai Hospital
Locations
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Fuwai Hospital
Beijing, Beijing Municipality, China
Xiehe Hospital
Beijing, Beijing Municipality, China
Guangdong General Hospital
Guangzhou, Guangdong, China
Shanghai Sixth People's Hospital
Shanghai, , China
General hospital of tianjin medical university
Tianjin, , China
Countries
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Central Contacts
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Facility Contacts
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Other Identifiers
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CIFuwaiHospital-2
Identifier Type: -
Identifier Source: org_study_id
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