Evaluate the Link Between the Characteristics of Oral Physiology and the Formation of the Food Bolus During the Consumption of Cereal Products in Elderly People

NCT ID: NCT03227887

Last Updated: 2017-07-24

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

Get a concise snapshot of the trial, including recruitment status, study phase, enrollment targets, and key timeline milestones.

Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

20 participants

Study Classification

INTERVENTIONAL

Study Start Date

2016-06-06

Study Completion Date

2016-09-30

Brief Summary

Review the sponsor-provided synopsis that highlights what the study is about and why it is being conducted.

The aim of this study is to understand how foods such as Sponge cake or Brioche are broken down in the mouth. More specifically, investigators wish to evaluate the link between oral physiology (salivation and mastication) and (i) formation of the food bolus during the consumption of Sponge cake or Brioche, that is to say the way in which the food is broken down to be swallowed (ii) mouthfeel during the consumption of Sponge cake or Brioche, meaning the sensations that participant feel when they eat these products.

The study will take place at the INRA in Dijon during 7 one-hour sessions spread over 3 months. The first session will allow us to characterise the chewing behaviour of the subjects and their salivation, and will enable us to train them in the instructions for the following sessions. The 6 other sessions will allow us to study the structure of the food bolus while being formed and the mouthfeel of the foods in the project.

In the first session:

* Two samples of saliva will be taken
* A video will be made of subjects eating Sponge cake or Brioche
* Subjects will be trained in exercises for the following sessions - this will consist in chewing the study foods and spitting them out on the experimenter's signal.

During the 6 other sessions, subjects will be asked to:

* Chew one of the study foods and spit it out on the signal of the experimenter.
* Evaluate the mouthfeel while eating Sponge cake or Brioche by answering different questions. This test will be done during 4 of the 6 sessions.

Detailed Description

Dive into the extended narrative that explains the scientific background, objectives, and procedures in greater depth.

Conditions

See the medical conditions and disease areas that this research is targeting or investigating.

Old Person

Study Design

Understand how the trial is structured, including allocation methods, masking strategies, primary purpose, and other design elements.

Allocation Method

NON_RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

OTHER

Blinding Strategy

NONE

Study Groups

Review each arm or cohort in the study, along with the interventions and objectives associated with them.

Good chewing ability

Group Type ACTIVE_COMPARATOR

Two samples of saliva

Intervention Type OTHER

1. Without stimulation : the 1st will be used to measure the flow of naturally secreted saliva
2. With stimulation: The 2nd will be used to measure the flow and viscosity of the saliva secreted after stimulation

Chewing behaviour

Intervention Type OTHER

Measure the time taken by the subjects to chew the food and the number of bites they use before swallowing The test will be done twice.

Study of the food bolus

Intervention Type OTHER

2 tests:

1. Evaluate using a compression test the structure of each bolus to determine their degree of destructuration over time Measure the quantity of the saliva incorporated
2. The bolus will be analysed visually

Mouthfeel

Intervention Type OTHER

Describe the mouthfeel by answering a paper questionnaire after consumption of the cereal products

Impaired chewing ability

Group Type EXPERIMENTAL

Two samples of saliva

Intervention Type OTHER

1. Without stimulation : the 1st will be used to measure the flow of naturally secreted saliva
2. With stimulation: The 2nd will be used to measure the flow and viscosity of the saliva secreted after stimulation

Chewing behaviour

Intervention Type OTHER

Measure the time taken by the subjects to chew the food and the number of bites they use before swallowing The test will be done twice.

Study of the food bolus

Intervention Type OTHER

2 tests:

1. Evaluate using a compression test the structure of each bolus to determine their degree of destructuration over time Measure the quantity of the saliva incorporated
2. The bolus will be analysed visually

Mouthfeel

Intervention Type OTHER

Describe the mouthfeel by answering a paper questionnaire after consumption of the cereal products

Interventions

Learn about the drugs, procedures, or behavioral strategies being tested and how they are applied within this trial.

Two samples of saliva

1. Without stimulation : the 1st will be used to measure the flow of naturally secreted saliva
2. With stimulation: The 2nd will be used to measure the flow and viscosity of the saliva secreted after stimulation

Intervention Type OTHER

Chewing behaviour

Measure the time taken by the subjects to chew the food and the number of bites they use before swallowing The test will be done twice.

Intervention Type OTHER

Study of the food bolus

2 tests:

1. Evaluate using a compression test the structure of each bolus to determine their degree of destructuration over time Measure the quantity of the saliva incorporated
2. The bolus will be analysed visually

Intervention Type OTHER

Mouthfeel

Describe the mouthfeel by answering a paper questionnaire after consumption of the cereal products

Intervention Type OTHER

Eligibility Criteria

Check the participation requirements, including inclusion and exclusion rules, age limits, and whether healthy volunteers are accepted.

Inclusion Criteria

* persons who have provided written consent
* Age ≥ 65 years old
* Persons living at home
* Persons who can travel independently

Exclusion Criteria

* Adults under guardianship
* Persons without health insurance cover
* Persons in hospital
* Persons in institutions
* Persons whose Mini-Mental State Examination (MMSE) is \< 24
* Persons requiring enteral or parenteral nutrition
* Persons who in the previous 12 months received € 4500 for taking part in clinical trials, including the present study
* Persons in a period of exclusion of a previous study
* Food allergies (cereal products in particular)
Minimum Eligible Age

65 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

Meet the organizations funding or collaborating on the study and learn about their roles.

Centre Hospitalier Universitaire Dijon

OTHER

Sponsor Role lead

Responsible Party

Identify the individual or organization who holds primary responsibility for the study information submitted to regulators.

Responsibility Role SPONSOR

Locations

Explore where the study is taking place and check the recruitment status at each participating site.

CHU Dijon Bourgogne

Dijon, , France

Site Status

Countries

Review the countries where the study has at least one active or historical site.

France

Other Identifiers

Review additional registry numbers or institutional identifiers associated with this trial.

VVW Alimassens cereales

Identifier Type: -

Identifier Source: org_study_id

More Related Trials

Additional clinical trials that may be relevant based on similarity analysis.

Effect of Carbonated Water on Swallowing
NCT06563960 ENROLLING_BY_INVITATION NA
Lollipop on Gastric Emptying
NCT04092049 COMPLETED NA