Inflammation in an Ultra Endurance Race

NCT ID: NCT03194035

Last Updated: 2018-08-03

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Total Enrollment

25 participants

Study Classification

OBSERVATIONAL

Study Start Date

2018-10-01

Study Completion Date

2018-10-17

Brief Summary

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The aim of this study is to study the per and post-exertional variations of the pro and anti inflammatory markers during an ultra-endurance race in healthy volunteers.

Detailed Description

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Study per and post-exertional changes in proinflammatory biological (IL1, IL6, TNF alpha, HMG beta1 and CRP) and anti inflammatory parameters (IL4, IL10 and IL13, TGF beta, LPS, lipoproteins, lipids) during an ultra endurance race.

Conditions

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Inflammation Inflammatory Response

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Interventions

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blood sample

Study per and post-exertional changes in proinflammatory biological (IL1, IL6, TNF alpha, HMG beta1 and CRP) and anti inflammatory parameters (IL4, IL10 and IL13, TGF beta, LPS, lipoproteins, lipids) during an ultra endurance race.

Intervention Type BIOLOGICAL

Eligibility Criteria

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Inclusion Criteria

1. Male older than 18 years,
2. Completion of an ultra-endurance race (distance greater than 50 kilometers) during the 24 months preceding the race.
3. Affiliation or beneficiary of a social security.

Exclusion Criteria

1. Age lower than 18 years,
2. Subjects with a medical history (pulmonary pathology, cardiac, hypertension) or with a significant chronic inflammatory disease observed during the inclusion visit (the day before the race).
3. Female.
Minimum Eligible Age

18 Years

Maximum Eligible Age

70 Years

Eligible Sex

MALE

Accepts Healthy Volunteers

Yes

Sponsors

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Hôpital Necker-Enfants Malades

OTHER

Sponsor Role lead

Responsible Party

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Romain Jouffroy

Principal Investigator

Responsibility Role PRINCIPAL_INVESTIGATOR

Other Identifiers

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TRAIL-INFLA

Identifier Type: -

Identifier Source: org_study_id

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