Autonomic Nervous System, Fatigue and Intolerance to Physical Training, and Overtraining in High-Level Athletes

NCT ID: NCT01463761

Last Updated: 2013-03-06

Basic Information

• Recruitment Status: COMPLETED
• Total Enrollment: 131 participants
• Study Classification: OBSERVATIONAL
• Study Start Date: 2010-07-31
• Study Completion Date: 2012-12-31

Brief Summary

Sports training aims to enhance an athlete's performance (overcompensation). To do that, the athlete must go through periods of fatigue and lower performance (overreaching). When the training plan is balanced, this fatigue is short and reversible.If the training load is too heavy or if recuperation periods are too short, it can lead to persistence fatigue that may only be reversible in the long term. This state of fatigue is part of the broader clinical picture of overtraining, which includes stark changes in performance as well as mood and sleep disorders. Many prediction and characterization methods based on biological markers have been evaluated, but they have not been put into practice in sports training due to obstacles such as reliability, interindividual variability and high costs. This study aims to evaluate a new approach based on the variability of an individual's heart rate (RR variability), which is a way of measuring autonomic nervous system (ASN) activity. It is non-invasive, low-cost, and has already proven useful in athlete health monitoring.

Detailed Description

The investigators propose to describe the variation of these ANS regulation factors over a full year, in a population of high-level athletes, in order to measure changes in regulation which may be predictive of potential fatigue and intolerance to physical training, if such a syndrome came to be observed among the study group.

Conditions

Athletes; Training; Fatigue

Study Design

• Observational Model Type: COHORT
• Study Time Perspective: PROSPECTIVE

Study Groups

high-level athletes

High-level athlete, enrolled in a Ministry-recognized Pôle

ANS activity

Intervention Type: DEVICE

This ANS activity is measured by nocturnal heart rates records with Holter ECG.

Interventions

ANS activity

This ANS activity is measured by nocturnal heart rates records with Holter ECG.

Intervention Type: DEVICE

Eligibility Criteria

Inclusion Criteria

• High-level athlete, enrolled in a Ministry-recognized Pôle
• Participant signed the informed consent form

Exclusion Criteria

• Confirmed current overtraining syndrome
• Known pregnancy on inclusion
• Athlete using cardio-inhibitor or cardio-accelerator drugs

• Minimum Eligible Age: 14 Years
• Eligible Sex: ALL
• Accepts Healthy Volunteers: Yes

Sponsors

Minister of Youth Affairs and Sports, France

OTHER_GOV

Sponsor Role: collaborator

Centre Hospitalier Universitaire de Saint Etienne

OTHER

Sponsor Role: lead

Responsible Party

Responsibility Role: SPONSOR

Principal Investigators

Frederic ROCHE, MD PhD

Role: PRINCIPAL_INVESTIGATOR

CHU de Saint-Etienne

Xavier BIGARD, MD PhD

Role: STUDY_CHAIR

Institut de Recherche Biomédicales des Armées

Locations

CH Albertville Moutiers

Albertville, , France

CHU de Besançon

Besançon, , France

Université Paris XIII

Bobigny, , France

CHU de Grenoble

Grenoble, , France

CHU de Pointe à Pitre

Pointe à Pitre, , France

CNSN Centre médical de Prémanon

Prémanon, , France

CHU de Saint-Etienne

Saint-Etienne, , France

CREPS Toulouse Midi Pyrénées

Toulouse, , France

Countries

France

Other Identifiers

2009-A00674-53

Identifier Type: OTHER

Identifier Source: secondary_id

0908073

Identifier Type: -

Identifier Source: org_study_id