Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
Get a concise snapshot of the trial, including recruitment status, study phase, enrollment targets, and key timeline milestones.
COMPLETED
239 participants
OBSERVATIONAL
2014-03-06
2014-10-18
Brief Summary
Review the sponsor-provided synopsis that highlights what the study is about and why it is being conducted.
Objective The study was aiming to explore epigenetic mechanism influences on macrosomic infants exposed to intrauterine hyperglycemia.
Design The investigators performed a genome-wide analysis of DNA methylation in cord blood from macrosomic infants born to women with gestational diabetes or infants with normal birth weight born to normal glucose-tolerant women in order to identify genes related to foetal growth or early adipose tissue development. The candidate genes were then validated using SEQUENOM MassARRAY after bisulfite conversion.
Related Clinical Trials
Explore similar clinical trials based on study characteristics and research focus.
Epigenetic Markers in Growth Restricted Human Pregnancies: a Case-controlled Study
NCT00510380
Maternal Obesity and Small for Gestational Age Infants
NCT00371657
Diagnosis and Management of Intrauterine Growth Restriction and Congenital Anomalies
NCT03398629
The Relationship Between Fetal Membrane Thickness and Fetal Chromosomal Aneuploidies
NCT06141213
Non-invasive Placental Chromosome Exploration of Intrauterine Growth Restriction
NCT05023161
Detailed Description
Dive into the extended narrative that explains the scientific background, objectives, and procedures in greater depth.
Conditions
See the medical conditions and disease areas that this research is targeting or investigating.
Study Design
Understand how the trial is structured, including allocation methods, masking strategies, primary purpose, and other design elements.
CASE_CONTROL
RETROSPECTIVE
Study Groups
Review each arm or cohort in the study, along with the interventions and objectives associated with them.
NGT-normal birth weight
No interventions assigned to this group
NGT-macrosomia
No interventions assigned to this group
GDM-normal birth weight
OGTT
75 g glucose tolerance test was provided to all pregnant women during 24-28 weeks.
GDM-macrosomia
OGTT
75 g glucose tolerance test was provided to all pregnant women during 24-28 weeks.
Interventions
Learn about the drugs, procedures, or behavioral strategies being tested and how they are applied within this trial.
OGTT
75 g glucose tolerance test was provided to all pregnant women during 24-28 weeks.
Eligibility Criteria
Check the participation requirements, including inclusion and exclusion rules, age limits, and whether healthy volunteers are accepted.
Inclusion Criteria
Exclusion Criteria
FEMALE
No
Sponsors
Meet the organizations funding or collaborating on the study and learn about their roles.
Peking University First Hospital
OTHER
Responsible Party
Identify the individual or organization who holds primary responsibility for the study information submitted to regulators.
Jie Yan
Other Identifiers
Review additional registry numbers or institutional identifiers associated with this trial.
2013572
Identifier Type: -
Identifier Source: org_study_id
More Related Trials
Additional clinical trials that may be relevant based on similarity analysis.