Validation of a Newly Developed Sham Press Needle

NCT ID: NCT03157024

Last Updated: 2017-05-17

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

84 participants

Study Classification

INTERVENTIONAL

Study Start Date

2016-04-04

Study Completion Date

2016-06-02

Brief Summary

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This is a single blind randomised controlled trial involving healthy volunteers to determine feasibility and blinding property of two types of sham press needles.

Detailed Description

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A total of 84 healthy volunteers will be recruited and randomly allocated to receive real needles (RN), previously validated Kim Sham needles (KS), or newly developed Ring Sham needles (RS) at a 1:1:1 ratio. Acupuncture sensation, blinding, and feasibility in a future clinical trial will be measured along with other physiological measurements including tactile sensitivity, interoceptive sensitivity, and electrodermal activity.

Conditions

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Healthy

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

DEVICE_FEASIBILITY

Blinding Strategy

SINGLE

Participants

Study Groups

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Sham Press Needle - Ring Sham (RS)

A sterilised stainless steel press needle that only has the ring-shaped head of needle without needle body has three layers of adhesive tape. Between the first and second layer is the head of needle to support needle body while maintaining identical appearance and the third layer is attached to skin. RS will be placed on 1 cm medial to acupoint LI11 and ear wrist, a non-specific control auricular acupoint used in the previous literature of the non-dominant side. An acupoint detector (personal TENS electronic acupuncture, Hammtek Korea, Seoul, Korea) will be used to locate points with lower skin impedance than those nearby.

Group Type EXPERIMENTAL

Ring Sham (RS)

Intervention Type DEVICE

Real Needle (RN)

A sterilised stainless steel press needle (diameter 0.18 mm X length 1.5 mm, Dongbang Acupuncture Inc., Boryeong, Chungcheongnam-do, Korea) has three layers of adhesive tape. Between the first and second layer is the head of needle to support needle body and the third layer is attached to skin. RN will be placed on acupoint LI11 and ear shenmen of the non-dominant side. An acupoint detector (personal TENS electronic acupuncture, Hammtek Korea, Seoul, Korea) will be used to locate points with lower skin impedance than those nearby.

Group Type ACTIVE_COMPARATOR

Real Needle (RN)

Intervention Type DEVICE

Kim Sham (KS)

A sterilised stainless steel press needle (diameter 0.18 mm X length 1.5 mm, Dongbang Acupuncture Inc., Boryeong, Chungcheongnam-do, Korea) with a blunted tip has three layers of adhesive tape. Between the first and second layer is the head of needle to support needle body while maintaining identical appearance and the third layer is attached to skin. KS will be placed on 1 cm medial to acupoint LI11 and ear wrist, a non-specific control auricular acupoint used in the previous literature of the non-dominant side. An acupoint detector (personal TENS electronic acupuncture, Hammtek Korea, Seoul, Korea) will be used to locate points with lower skin impedance than those nearby.

Group Type SHAM_COMPARATOR

Kim Sham (KS)

Intervention Type DEVICE

Interventions

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Ring Sham (RS)

Intervention Type DEVICE

Real Needle (RN)

Intervention Type DEVICE

Kim Sham (KS)

Intervention Type DEVICE

Eligibility Criteria

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Inclusion Criteria

* age over 18
* not participating in other clinical studies at the time of study participation
* voluntary participation

* pregnancy or breast-feeding at the time of study participation
* open sores or skin diseases on the non-dominant elbow or ear where needles would be placed
* having taken analgesics in 24 hours before participation
* any other diseases or conditions that might prevent the participant from receiving acupuncture
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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National Research Foundation of Korea

OTHER

Sponsor Role collaborator

Kyunghee University

OTHER

Sponsor Role lead

Responsible Party

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Hyangsook Lee, KMD, PhD

Professor

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Hi-Joon Park, KMD, PhD

Role: STUDY_DIRECTOR

Kyunghee University

Locations

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Acupuncture & Meridian Science Research Centre, Kyung Hee University

Seoul, , South Korea

Site Status

Countries

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South Korea

References

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Kim S. Creating an instrument for a successful double-blind acupuncture placebo. J Acupunct Meridian Stud. 2008 Sep;1(1):36-41. doi: 10.1016/S2005-2901(09)60005-4. Epub 2009 Mar 24.

Reference Type BACKGROUND
PMID: 20633453 (View on PubMed)

Lee H, Bang H, Kim Y, Park J, Lee S, Lee H, Park HJ. Non-penetrating sham needle, is it an adequate sham control in acupuncture research? Complement Ther Med. 2011 Jan;19 Suppl 1:S41-8. doi: 10.1016/j.ctim.2010.12.002. Epub 2010 Dec 23.

Reference Type BACKGROUND
PMID: 21195294 (View on PubMed)

Bang H, Ni L, Davis CE. Assessment of blinding in clinical trials. Control Clin Trials. 2004 Apr;25(2):143-56. doi: 10.1016/j.cct.2003.10.016.

Reference Type BACKGROUND
PMID: 15020033 (View on PubMed)

Moroz A, Freed B, Tiedemann L, Bang H, Howell M, Park JJ. Blinding measured: a systematic review of randomized controlled trials of acupuncture. Evid Based Complement Alternat Med. 2013;2013:708251. doi: 10.1155/2013/708251. Epub 2013 Mar 3.

Reference Type BACKGROUND
PMID: 23533515 (View on PubMed)

Kim Y, Park J, Lee H, Bang H, Park HJ. Content validity of an acupuncture sensation questionnaire. J Altern Complement Med. 2008 Oct;14(8):957-63. doi: 10.1089/acm.2007.0565.

Reference Type BACKGROUND
PMID: 18925869 (View on PubMed)

Kim S, Lee S, Choi S, Park J, Kim S. Discrimination accuracy between real and sham press needles in the hands. Acupunct Med. 2015 Aug;33(4):293-8. doi: 10.1136/acupmed-2014-010678. Epub 2015 Jun 4.

Reference Type BACKGROUND
PMID: 26044714 (View on PubMed)

Wang SM, Maranets I, Weinberg ME, Caldwell-Andrews AA, Kain ZN. Parental auricular acupuncture as an adjunct for parental presence during induction of anesthesia. Anesthesiology. 2004 Jun;100(6):1399-404. doi: 10.1097/00000542-200406000-00011.

Reference Type BACKGROUND
PMID: 15166558 (View on PubMed)

Wang SM, Dezinno P, Lin EC, Lin H, Yue JJ, Berman MR, Braveman F, Kain ZN. Auricular acupuncture as a treatment for pregnant women who have low back and posterior pelvic pain: a pilot study. Am J Obstet Gynecol. 2009 Sep;201(3):271.e1-9. doi: 10.1016/j.ajog.2009.04.028. Epub 2009 Jun 26.

Reference Type BACKGROUND
PMID: 19560110 (View on PubMed)

Schandry R. Heart beat perception and emotional experience. Psychophysiology. 1981 Jul;18(4):483-8. doi: 10.1111/j.1469-8986.1981.tb02486.x. No abstract available.

Reference Type BACKGROUND
PMID: 7267933 (View on PubMed)

Vincent C, Lewith G. Placebo controls for acupuncture studies. J R Soc Med. 1995 Apr;88(4):199-202.

Reference Type BACKGROUND
PMID: 7745565 (View on PubMed)

Other Identifiers

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KHSIRB-16-009

Identifier Type: -

Identifier Source: org_study_id

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