Efficacy and Safety Study of Individualized and Standardized Acupuncture Treatment for Low Back Pain

NCT ID: NCT01570127

Last Updated: 2012-04-06

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Clinical Phase

PHASE2

Total Enrollment

276 participants

Study Classification

INTERVENTIONAL

Study Start Date

2010-10-31

Study Completion Date

2012-12-31

Brief Summary

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The purpose of this study is to determine whether acupuncture treatment(Individualized \& Standardized Acupuncture) is more effective than control (sham acupuncture or no treatment) and also whether individualized acupuncture is more effective than standardized acupuncture.

Detailed Description

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To determine whether individualized acupuncture is more effective than standardized acupuncture, 276 Low Back Pain patients will be recruited and randomly assigned to 4 separate groups.

Experimental groups(Individualized Acupuncture Group and Standardized Acupuncture Group) and Control groups (Sham acupuncture and waiting list)

The change of pain and physical functions will be compared among the four groups.

So the efficacy of acupuncture, and the best acupuncture treatment model will be determined. Also in addition, safety and abnormal reactions of acupuncture treatments will be evaluated.

Conditions

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Low Back Pain

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

TRIPLE

Participants Investigators Outcome Assessors

Study Groups

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Individualized Acupuncture

The patients in this group received individualized acupuncture prescribed by a certified Korean Medicine Doctor with more than 6 years of oriental medicine college education and 2 years of clinical experience. The acupuncture formulas were composed based on the pattern diagnosis, which is an unique diagnosis system of Oriental Medicine.

Group Type EXPERIMENTAL

Individualized Acupuncture

Intervention Type PROCEDURE

The treatment was applied twice a week for 20 minutes for 6 weeks(12sessions)

Standardized Acupuncture

The patients in this group received standardized acupuncture treatment using the same acupuncture points, applied by a certified Korean Medicine Doctor with more than 6 years of oriental medicine college education and 2 years of clinical experience. The acupuncture formulas were composed based on literature review of RCTs.

Group Type EXPERIMENTAL

Standardized Acupuncture

Intervention Type PROCEDURE

The treatment was applied twice a week for 20 minutes for 6 weeks(12sessions) 8 Acupuncture points, GV4, GV3, BL24(bilateral), BL25(bilateral) and GB30(bilateral) were used for all the patients assigned to this group. Sterile Stainless Steel(25mm x 40mm) disposable acupuncture needles manufactured by Dong-Bang Acupuncture Co.(Korea) were used.

Sham acupuncture

Non-penetrating acupuncture device, Park-sham acupuncture, was applied to the patients. The appearance of the acupuncture is same but the needles do not penetrate the skin.

Group Type SHAM_COMPARATOR

Sham Acupuncture

Intervention Type PROCEDURE

The treatment was applied twice a week for 6 weeks(12sessions). The sham acupuncture was applied on the 8 same acupuncture points as in the standardized acupuncture group, GV4, GV3, BL24(bilateral), BL25(bilateral) and GB30(bilateral). Each session was 20 minutes long.

Waiting

No interventions were applied to the patients in this group. Only assessments were made at each visit.

Group Type NO_INTERVENTION

Waiting

Intervention Type OTHER

No interventions were applied to the patients in this group.

Interventions

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Individualized Acupuncture

The treatment was applied twice a week for 20 minutes for 6 weeks(12sessions)

Intervention Type PROCEDURE

Standardized Acupuncture

The treatment was applied twice a week for 20 minutes for 6 weeks(12sessions) 8 Acupuncture points, GV4, GV3, BL24(bilateral), BL25(bilateral) and GB30(bilateral) were used for all the patients assigned to this group. Sterile Stainless Steel(25mm x 40mm) disposable acupuncture needles manufactured by Dong-Bang Acupuncture Co.(Korea) were used.

Intervention Type PROCEDURE

Sham Acupuncture

The treatment was applied twice a week for 6 weeks(12sessions). The sham acupuncture was applied on the 8 same acupuncture points as in the standardized acupuncture group, GV4, GV3, BL24(bilateral), BL25(bilateral) and GB30(bilateral). Each session was 20 minutes long.

Intervention Type PROCEDURE

Waiting

No interventions were applied to the patients in this group.

Intervention Type OTHER

Other Intervention Names

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Park Sham Device No interventions

Eligibility Criteria

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Inclusion Criteria

* Male and female patients suffering Low Back Pain.
* Patients classified as Class 1(pain in the lumbar area, without radiation below the gluteal fold and in the absence of neurologic signs) or Class 2(Low back pain with radiation of pain not beyond the knee, no neurological signs) according to the Quebec Task Force System
* Suffering pain which is more than 40mm on VAS(Visual Analog Scale)
* Voluntary participants who have completed the consent.

Exclusion Criteria

* Low back trauma history within 6 months.
* Low back surgery history within 6 months.
* Low back pain caused by malignancy, inflammatory disease, fibromyalgia, vertebral fracture, infection, juvenile scoliosis or congenital malformation.
* Pain in other parts of the body more severe than low back pain.
* Mental problems that can influence the pain or results of questionnaire.
* Diseases that can interfere absorption, metabolism and excretion of medicine.
* History of alcohol or drug abuse within 12 months of the study.
* Pregnant, breastfeeding or childbearing aged women who are not using any birth control methods.
Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Ministry of Health & Welfare, Korea

OTHER_GOV

Sponsor Role collaborator

Gachon University Gil Medical Center

OTHER

Sponsor Role collaborator

Dongwoo Nam

OTHER

Sponsor Role lead

Responsible Party

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Dongwoo Nam

Assistant Professor

Responsibility Role SPONSOR_INVESTIGATOR

Principal Investigators

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Jae-Dong Lee, Ph.D

Role: STUDY_CHAIR

Kyunghee University Medical Center

Locations

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Kyung Hee University Oriental Medicine Hospital

Seoul, Seoul, South Korea

Site Status RECRUITING

Countries

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South Korea

Central Contacts

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Dongwoo Nam, Ph.D.

Role: CONTACT

+82-2-958-1827

Facility Contacts

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Dongwoo Nam, Ph.D

Role: primary

+82-2-958-1827

Other Identifiers

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KOMCIRB-02-20101130-02

Identifier Type: -

Identifier Source: org_study_id

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