Quantitative Evaluation of Bitter Taste in Obesity

NCT ID: NCT03149666

Last Updated: 2017-05-11

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

262 participants

Study Classification

OBSERVATIONAL

Study Start Date

2015-02-01

Study Completion Date

2016-07-01

Brief Summary

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Although taste influences food choices and favours diseases like obesity, there is no consensus about the existence of correlations between bitterness and anthropometric variables. Also, an electronic-based method for data collection could provide a more appropriate way for the evaluation of taste perception and save time.

The objective is to search for correlations between bitterness and anthropometric variables.

Detailed Description

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A cross-sectional study evaluating correlations between the bitterness rates given on a generalized Labeled Magnitude Scale, anthropometrics and other variables. Bitterness perceptions at the tip of the tongue (TOTp) and at the whole mouth (WMp) were recorded using a locally developed novel cloud-based software (Cloud-gLMS). The ANCOVA test was adjusted using TOTp and WMp as dependent variables and age, height, weight, BMI, gender, waist circumference, alcohol intake, comorbidities, and use of medications as independent variables.

Conditions

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Obesity

Study Design

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Observational Model Type

OTHER

Study Time Perspective

CROSS_SECTIONAL

Study Groups

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Evaluation of bitter taste

Participants will be evaluated as to the intensity of bitter taste when performing watery mouthwash with quinine.

No interventions assigned to this group

Eligibility Criteria

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Inclusion Criteria

* Weight limit of 150 kg and who are able to read the text with the guidelines on how to be punctuated the sensation of bitter in the generalized labeled scale.

Exclusion Criteria

* Being a relative of the first degree of a patient already included in the research, tobacco in the forms of cigarettes, pipes and cigars in the last 30 days, presence of coryza, nasal congestion or frequent sneezing, dental treatment on the same day of the research. Being a dementia sufferer, having an altered, drowsy level of consciousness. Show upper limb tremor visible.
Minimum Eligible Age

18 Years

Maximum Eligible Age

59 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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University of Sao Paulo

OTHER

Sponsor Role lead

Responsible Party

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Julio Sergio Marchini

Principal Investigator

Responsibility Role PRINCIPAL_INVESTIGATOR

References

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Reiter ER, DiNardo LJ, Costanzo RM. Toxic effects on gustatory function. Adv Otorhinolaryngol. 2006;63:265-277. doi: 10.1159/000093765.

Reference Type BACKGROUND
PMID: 16733344 (View on PubMed)

Sharma K, Kaur GK. PTC bitter taste genetic polymorphism, food choices, physical growth in body height and body fat related traits among adolescent girls from Kangra Valley, Himachal Pradesh (India). Ann Hum Biol. 2014 Jan-Feb;41(1):29-39. doi: 10.3109/03014460.2013.822929. Epub 2013 Aug 12.

Reference Type BACKGROUND
PMID: 23937293 (View on PubMed)

Keller KL, Adise S. Variation in the Ability to Taste Bitter Thiourea Compounds: Implications for Food Acceptance, Dietary Intake, and Obesity Risk in Children. Annu Rev Nutr. 2016 Jul 17;36:157-82. doi: 10.1146/annurev-nutr-071715-050916. Epub 2016 Apr 6.

Reference Type BACKGROUND
PMID: 27070900 (View on PubMed)

Bartoshuk LM, Duffy VB, Green BG, Hoffman HJ, Ko CW, Lucchina LA, Marks LE, Snyder DJ, Weiffenbach JM. Valid across-group comparisons with labeled scales: the gLMS versus magnitude matching. Physiol Behav. 2004 Aug;82(1):109-14. doi: 10.1016/j.physbeh.2004.02.033.

Reference Type BACKGROUND
PMID: 15234598 (View on PubMed)

Segovia C, Hutchinson I, Laing DG, Jinks AL. A quantitative study of fungiform papillae and taste pore density in adults and children. Brain Res Dev Brain Res. 2002 Oct 20;138(2):135-46. doi: 10.1016/s0165-3806(02)00463-7.

Reference Type BACKGROUND
PMID: 12354641 (View on PubMed)

Other Identifiers

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HCRP 924/2015

Identifier Type: -

Identifier Source: org_study_id

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