Study of the Effectiveness of Cervical Ripening Balloon With and Without Oxytocin

NCT ID: NCT03138252

Last Updated: 2022-05-04

Study Results

Results available

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Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

PHASE3

Total Enrollment

180 participants

Study Classification

INTERVENTIONAL

Study Start Date

2014-11-30

Study Completion Date

2017-07-31

Brief Summary

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Study Purpose: The purpose of this study is to determine the optimal method for induction of labor in multiparous women who present with an unfavorable cervix.

Hypothesis: Our hypothesis is that using oxytocin while the cervical ripening balloon is in place will result in more rapid labor courses, without increasing morbidity or increasing the need for operative delivery.

Detailed Description

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Conditions

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Cervical Ripening Induction of Labor Multiparity

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

NONE

Study Groups

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Cervical Ripening Balloon Alone

Multiparous women will begin cervical ripening with a cervical ripening balloon alone. After the balloon is expelled or removed, induction of labor will proceed with pitocin per standard protocol at MacDonald Women's Hospital.

Group Type ACTIVE_COMPARATOR

Oxytocin

Intervention Type DRUG

Cervical Ripening Balloon + Oxytocin

Multiparous women will begin cervical ripening with a cervical ripening balloon and simultaneous oxytocin. After the balloon is expelled or removed, induction of labor will proceed with pitocin per standard protocol at MacDonald Women's Hospital.

Group Type ACTIVE_COMPARATOR

Oxytocin

Intervention Type DRUG

Interventions

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Oxytocin

Intervention Type DRUG

Eligibility Criteria

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Inclusion Criteria

* Age \> 18 years
* Gestational age \> 34 + 0/7 weeks
* Prior spontaneous vaginal delivery
* Clinical or U/S EFW of \<4500 grams
* Singleton gestation
* Cervical dilation \<2 cm

Exclusion Criteria

* Any contraindication to cervical ripening balloon, pitocin, or vaginal delivery
* Placenta within 2 cm of cervical os
* Placental abruption, chorioamninoitis, or systemic infection prior to induction
* Rupture of membranes prior to induction -\>1 prior C/S
Minimum Eligible Age

18 Years

Eligible Sex

FEMALE

Accepts Healthy Volunteers

Yes

Sponsors

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University Hospitals Cleveland Medical Center

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Locations

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Alison Bauer

Cleveland, Ohio, United States

Site Status

Countries

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United States

Provided Documents

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Document Type: Study Protocol and Statistical Analysis Plan

View Document

Other Identifiers

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CRB + Oxytocin

Identifier Type: -

Identifier Source: org_study_id

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