Labor Induction With Dinoprostone in Oppose to Cervical Ripening Balloon as a Factor of BMI.

NCT ID: NCT03033264

Last Updated: 2020-10-19

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

164 participants

Study Classification

INTERVENTIONAL

Study Start Date

2017-01-01

Study Completion Date

2020-10-01

Brief Summary

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Women with a BMI\>30 and women with a BMI\<30 will be divided in a randomized controlled manor to 4 groups depending on the mode of labor induction and BMI value:

1. Dinoprostone in women with a BMI\>30.
2. Dinoprostone in women with a BMI\<30.
3. Cervical ripening balloon in women with a BMI\>30.
4. Cervical ripening balloon in women with a BMI\<30. The subjects will be followed until labor, and information regarding the success of induction, mode of delivery and time of delivery will be collected from patients' electronic files.

Detailed Description

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The study is a randomized controlled test in which women with a BMI\>30 and women with a BMI\<30 will sign an informed consent and then divided to 4 groups depending on the mode of labor induction and BMI value:

1. Dinoprostone in women with a BMI\>30.
2. Dinoprostone in women with a BMI\<30.
3. Cervical ripening balloon in women with a BMI\>30.
4. Cervical ripening balloon in women with a BMI\<30. All subjects participating in the study will be induced for obstetrical indications alone.

The subjects will be followed until labor, and information regarding the success of induction, mode of delivery and time of delivery will be collected from patients' electronic files.

The participants will finish participation in the study after delivery.

Conditions

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Induction of Labor

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

NONE

Study Groups

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BMI>30+Dinoprostone

Women with a BMI\>30 at term that will be induced for obstetrical indications with 10 mg of a Dinoprostone vaginal insert.

Group Type EXPERIMENTAL

Dinoprostone

Intervention Type DRUG

10 mg of a Dinoprostone vaginal insert.

BMI<30+Dinoprostone

Women with a BMI\<30 at term that will be induced for obstetrical indications with 10 mg of a Dinoprostone vaginal insert.

Group Type EXPERIMENTAL

Dinoprostone

Intervention Type DRUG

10 mg of a Dinoprostone vaginal insert.

BMI>30+Cervical ripening balloon

Women with a BMI\>30 at term that will be induced for obstetrical indications with a double lumen cervical ripening balloon.

Group Type EXPERIMENTAL

Double lumen cervical ripening balloon.

Intervention Type DEVICE

Double lumen cervical ripening balloon.

BMI<30+Cervical ripening balloon

Women with a BMI\<30 at term that will be induced for obstetrical indications with a double lumen cervical ripening balloon.

Group Type EXPERIMENTAL

Double lumen cervical ripening balloon.

Intervention Type DEVICE

Double lumen cervical ripening balloon.

Interventions

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Dinoprostone

10 mg of a Dinoprostone vaginal insert.

Intervention Type DRUG

Double lumen cervical ripening balloon.

Double lumen cervical ripening balloon.

Intervention Type DEVICE

Other Intervention Names

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Prostaglandin E2

Eligibility Criteria

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Inclusion Criteria

* Any pregnant woman at term with an obstetric indication for labor induction.

Exclusion Criteria

* Previous cesarean section.
* Positive Oxytocin challenge test.
* Positive contraction stress test.
Minimum Eligible Age

18 Years

Maximum Eligible Age

44 Years

Eligible Sex

FEMALE

Accepts Healthy Volunteers

Yes

Sponsors

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Rambam Health Care Campus

OTHER

Sponsor Role lead

Responsible Party

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ROY LAUTERBACH MD

Principal Investigator

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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ROY LAUTERBACH, MD

Role: PRINCIPAL_INVESTIGATOR

Rambam Health Care Campus

Locations

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Rambam health care campus

Haifa, , Israel

Site Status

Countries

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Israel

References

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de Vaan MD, Ten Eikelder ML, Jozwiak M, Palmer KR, Davies-Tuck M, Bloemenkamp KW, Mol BWJ, Boulvain M. Mechanical methods for induction of labour. Cochrane Database Syst Rev. 2023 Mar 30;3(3):CD001233. doi: 10.1002/14651858.CD001233.pub4.

Reference Type DERIVED
PMID: 36996264 (View on PubMed)

Other Identifiers

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0192-19-RMB

Identifier Type: -

Identifier Source: org_study_id

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