Double Balloon Catheter Versus Dinoprostone Vaginal Insert for Cervical Ripening.

NCT ID: NCT01170819

Last Updated: 2011-12-13

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

PHASE4

Total Enrollment

210 participants

Study Classification

INTERVENTIONAL

Study Start Date

2010-06-30

Study Completion Date

2011-12-31

Brief Summary

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To compare the efficacy of transcervical double balloon catheters versus controlled release dinoprostone vaginal inserts for pre-induction cervical ripening in term women with unfavourable cervices.

Detailed Description

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Conditions

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Cervical Ripening Labor Induction

Keywords

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Cervical ripening Induction of labor Prostaglandins Mechanical methods Balloon catheter

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

NONE

Study Groups

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Dinoprostone Vaginal Insert

Group Type ACTIVE_COMPARATOR

Dinoprostone 10 mg controlled-release vaginal insert

Intervention Type DRUG

Vaginal insert is placed in the posterior vaginal fornix for a maximum period of 24 hours.

Double Balloon Catheter

Group Type EXPERIMENTAL

Double balloon catheter

Intervention Type DEVICE

The balloons either side of the cervix are inflated with 50 ml of water. The catheter is removed after 12 hours if spontaneous expulsion has not occurred.

Interventions

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Double balloon catheter

The balloons either side of the cervix are inflated with 50 ml of water. The catheter is removed after 12 hours if spontaneous expulsion has not occurred.

Intervention Type DEVICE

Dinoprostone 10 mg controlled-release vaginal insert

Vaginal insert is placed in the posterior vaginal fornix for a maximum period of 24 hours.

Intervention Type DRUG

Other Intervention Names

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COOK CERVICAL BALLOON, COOK UROLOGICAL INC. US PROPESS®, Ferring Pharmaceuticals

Eligibility Criteria

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Inclusion Criteria

* singleton gestation
* gestational age greater than 34 weeks
* cephalic presentation
* intact membranes
* Bishop score of ≤4
* reactive fetal heart rate (FHR) pattern on admission

Exclusion Criteria

* any condition precluding vaginal delivery
* any contraindication to receiving prostaglandins, including history of asthma, glaucoma, or cardiac or cardiovascular disease
* previous cesarean section or other uterine incision
Minimum Eligible Age

18 Years

Eligible Sex

FEMALE

Accepts Healthy Volunteers

No

Sponsors

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Università degli Studi dell'Insubria

OTHER

Sponsor Role lead

Responsible Party

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Antonella Cromi

PhD

Responsibility Role PRINCIPAL_INVESTIGATOR

Locations

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Del Ponte Hospital

Varese, , Italy

Site Status

Countries

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Italy

References

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de Vaan MD, Ten Eikelder ML, Jozwiak M, Palmer KR, Davies-Tuck M, Bloemenkamp KW, Mol BWJ, Boulvain M. Mechanical methods for induction of labour. Cochrane Database Syst Rev. 2023 Mar 30;3(3):CD001233. doi: 10.1002/14651858.CD001233.pub4.

Reference Type DERIVED
PMID: 36996264 (View on PubMed)

Other Identifiers

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1229

Identifier Type: -

Identifier Source: org_study_id