Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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TERMINATED
NA
48 participants
INTERVENTIONAL
2017-04-27
2020-10-23
Brief Summary
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Detailed Description
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Postural imbalance due to spinal deformity is usually measured on static radiographs, using standard X-rays. However, bipedal walk is characteristic from human being and the trunk is the main stabilizer.
Pathogenesis of spinal deformities remains undefined. To understand the different mechanisms involved in the pathological field, normal musculoskeletal performances of the spine, in static and dynamic conditions must be identified.
Ultra-low doses stereoradiography using the EOS system allows the acquisition of full-spine images in standing position. Furthermore, 3D reconstruction can also be create from both anteroom-posterior and lateral side view. Stereoradiography is used in clinical routine especially in children spinal deformities.
High resolution muscular MRI is the only device that can provide a detailed muscular analysis, with detection of abnormalities at an early stage. No mapping of normal paraspinal muscles has been yet realized, particularly regarding to rotatores muscles.
Motion analysis is the reference exam to analyse dynamic stability during gait. Several parameters reflecting stability during gait can be collected in different conditions. Recently, the "Dynamic Stability Margin" has been developed but no standard values especially in healthy children has been published.
Conditions
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Study Design
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NA
SINGLE_GROUP
OTHER
NONE
Study Groups
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healthy volunteers
EOS full-spine, MRI, gait analysis
EOS full-spine, MRI, gait analysis
full-spine stereoradiography, high-resolution spine muscle MRI and 3D gait analysis will be performed
Interventions
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EOS full-spine, MRI, gait analysis
full-spine stereoradiography, high-resolution spine muscle MRI and 3D gait analysis will be performed
Eligibility Criteria
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Inclusion Criteria
* Child or teenager, male or female, aged from 8 years to 17 years inclusive
* Adult, male or female, aged from 18 years to 40 years inclusive
* Realization of a preliminary medical examination
Exclusion Criteria
* Patient under guardianship or curatorship
* Inability to cooperate
* Pregnant woman
* Non affiliation to social security
* Subject with spinal and/or lower limbs affection
* Subject with antecedent of spinal and/or lower limbs surgery
* Subject with contraindication to MRI
* Refusal of the parent or the subject to be informed about a fortuitous discovery during the examinations of the exams
8 Years
40 Years
ALL
Yes
Sponsors
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Centre d'Investigation Clinique et Technologique 805
OTHER
Responsible Party
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Locations
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APHP Hopital raymond Poincaré
Garches, Île-de-France Region, France
Countries
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Other Identifiers
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2016-A01825-46
Identifier Type: -
Identifier Source: org_study_id
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