Volumetric Bone Mineral Density and it's Relationship With Osteoporotic Fractures in Parkinson's Disease

NCT ID: NCT03095690

Last Updated: 2018-03-13

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

90 participants

Study Classification

INTERVENTIONAL

Study Start Date

2016-01-07

Study Completion Date

2017-06-21

Brief Summary

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Idiopathic Parkinson's disease (IPD) is the second most frequent neurodegenerative disease. Its association with osteroporosis and fragility fracture is now clearly demonstrated, but the determinants of this osteoporosis are yet to be explained. Our aim was to study factors associated with volumetric bone mineral density (vBMD) and bone microstructure at the tibia and radius in IPD.

Detailed Description

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Conditions

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Idiopathic Parkinson's Disease

Study Design

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Allocation Method

NA

Intervention Model

SINGLE_GROUP

Primary Study Purpose

OTHER

Blinding Strategy

NONE

Study Groups

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Idiopathic Parkinson's Disease patients

High resolution peripheral scanner (HRpQCT).

Group Type OTHER

High resolution peripheral scanner (HRpQCT).

Intervention Type OTHER

radius and tibia osteodensitometry measurement

Interventions

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High resolution peripheral scanner (HRpQCT).

radius and tibia osteodensitometry measurement

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* Patients with idiopathic Parkinson's disease according to the criteria of the UKPDBB.
* Parkinson's disease of moderate severity (Index HOEHN and Yahr \<5)
* Patient can respond to questionnaires, with or without help

Exclusion Criteria

* Patients with active psychiatric illness preventing the realization of examinations
* Severe Parkinson's disease (Index HOEHN and Yahr ≥5 )
* Heavy-morbidity including heart failure NYHA\> 3 or chronic respiratory failure, terminal or severe renal impairment known dialyzed
* Pregnancy
Minimum Eligible Age

35 Years

Maximum Eligible Age

85 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Centre Hospitalier Régional d'Orléans

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Eric LESPESSAILLES, Ph

Role: PRINCIPAL_INVESTIGATOR

CHR d'ORLEANS

Locations

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CHR d'ORLEANS

Orléans, , France

Site Status

Countries

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France

Other Identifiers

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CHRO-2015-05

Identifier Type: -

Identifier Source: org_study_id

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