Double Carbapenem as Rescue Strategy for the Treatment of Carbapenemase-Producing Klebsiella Pneumoniae Infections
NCT ID: NCT03094494
Last Updated: 2017-03-29
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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COMPLETED
144 participants
OBSERVATIONAL
2012-11-01
2016-12-31
Brief Summary
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Detailed Description
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Conditions
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Study Design
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CASE_CONTROL
RETROSPECTIVE
Study Groups
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Double Carbapenem Group
Patients underwent Double carbapenem treatment
none intervention
none intervention
Standard Treatment Group
Patients who were not treated with the double carbapenem
none intervention
none intervention
Interventions
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none intervention
none intervention
Eligibility Criteria
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Inclusion Criteria
2. ICU admission between November 2012 and December 2015;
3. documented CR-Kp invasive infection;
4. targeted antibiotic therapy lasting ≥ 72 hours
Exclusion Criteria
2. Duration of antimicrobial therapy less than 72 hours
3. Data not completely available from the electronically medical chart
18 Years
ALL
No
Sponsors
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Fondazione Policlinico Universitario Agostino Gemelli IRCCS
OTHER
Responsible Party
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Dr. Gennaro De Pascale
MD
References
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De Pascale G, Martucci G, Montini L, Panarello G, Cutuli SL, Di Carlo D, Di Gravio V, Di Stefano R, Capitanio G, Vallecoccia MS, Polidori P, Spanu T, Arcadipane A, Antonelli M. Double carbapenem as a rescue strategy for the treatment of severe carbapenemase-producing Klebsiella pneumoniae infections: a two-center, matched case-control study. Crit Care. 2017 Jul 5;21(1):173. doi: 10.1186/s13054-017-1769-z.
Other Identifiers
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UCSC14669/15 359/2015
Identifier Type: -
Identifier Source: org_study_id
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