Comparison of ADR Using NBI Versus HD White Light Colonoscopy in Screening and Surveillance Colonoscopies
NCT ID: NCT03081975
Last Updated: 2018-03-20
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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COMPLETED
NA
500 participants
INTERVENTIONAL
2015-01-31
2017-12-31
Brief Summary
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Detailed Description
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Despite recent advances in endoscopic technology adenoma miss rate still is up to 20% and contributes to the occurrence of interval cancers. Therefore, improved imaging modalities have been introduced to increase adenoma detection rate (ADR) during screening and surveillance colonoscopies. Recently, narrow band imaging (NBI; Exera II series, Olympus Corporation) was not significantly better than high definition white light colonoscopy (WLC) for the detection of patients with colorectal polyps, or colorectal adenomas1. However, Olympus' current Exera III series is characterized by better illumination of the bowel lumen and may be associated with a higher ADR than high definition WLC.
Methods:
Investigators performed a prospective evaluation in patients referred to the Department of Interdisciplinary Endoscopy at Jena University Hospital for screening or surveillance colonoscopy between January and November 2015 in daily clinical practice. Colonoscopy was performed by use of HD-WLC or HD-NBI upon withdrawal of the colonoscope (Exera III series, Olympus Corporation).
Conditions
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Study Design
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RANDOMIZED
PARALLEL
DIAGNOSTIC
NONE
Study Groups
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HD white light
Colonoscopy was performed by use of HD-WLC or HD-NBI upon withdrawal
HD white light or NBI
Use of NBI or HD white light
HD narrow band imaging
Colonoscopy was performed by use of HD-WLC or HD-NBI upon withdrawal
HD white light or NBI
Use of NBI or HD white light
Interventions
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HD white light or NBI
Use of NBI or HD white light
Eligibility Criteria
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Inclusion Criteria
Exclusion Criteria
* Age under 55years
55 Years
ALL
Yes
Sponsors
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Jena University Hospital
OTHER
Responsible Party
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Martin Bürger
Narrow band imaging does not increase adenoma detection rate compared to high definition white light colonoscopy in screening and surveillance colonoscopies
Principal Investigators
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Carsten Schmidt, MD
Role: STUDY_DIRECTOR
University Clinic Jena
Locations
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University Clinic Jena
Jena, Thueringia, Germany
Countries
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References
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Burger M, Weber M, Petersen I, Stallmach A, Schmidt C. Adenoma detection rate using narrow-band imaging is inferior to high-definition white light colonoscopy in screening and surveillance colonoscopies in daily clinical care: A randomized controlled trial. Medicine (Baltimore). 2022 Aug 12;101(32):e29858. doi: 10.1097/MD.0000000000029858.
Other Identifiers
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NBI01
Identifier Type: -
Identifier Source: org_study_id
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