Biomarkers in Dyspnea

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

Get a concise snapshot of the trial, including recruitment status, study phase, enrollment targets, and key timeline milestones.

Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

34 participants

Study Classification

INTERVENTIONAL

Study Start Date

2017-11-23

Study Completion Date

2019-01-08

Brief Summary

Review the sponsor-provided synopsis that highlights what the study is about and why it is being conducted.

To explore biological mechanisms in human model of induced dyspnea, in order to remove the source of dyspnoea, to modify cerebral impact and to allow the development of targeted therapies.

Related Clinical Trials

Explore similar clinical trials based on study characteristics and research focus.

Diagnostic and Prognostic Value of New Biomarkers in Patients With Heart Disease

NCT01374880

Heart Failure Dyspnea Pulmonary Disease

UNKNOWN

Neurobiological and Immunological Mechanisms of Dyspnea in ALS (BIOPNEA)

NCT04332198

Shortness of Breath Dyspnea Amyotrophic Lateral Sclerosis

UNKNOWN NA

Exhaled Breath Metabolomic Biomarkers in the Acutely Breathless Patient

NCT03672994

Asthma COPD Heart Failure +3 more

COMPLETED

Optimization of Exhaled Biomarker Collection and Analysis

NCT05322785

Respiratory Disease Healthy

ENROLLING_BY_INVITATION NA

Diaphragmatic Function as a Biomarker

NCT05903001

Dyspnea; Asthmatic COPD Fibrosis +3 more

RECRUITING

Detailed Description

Dive into the extended narrative that explains the scientific background, objectives, and procedures in greater depth.

The aim of the study will be to identify a specific biology and immunology associated with dyspnoea. It will open therapeutic possibilities through a better understanding of the mechanisms of dyspnea.

Healthy volunteers will underwent two types of dyspnea. The subjects will be first familiar with both types of dyspnea and dyspnea measurement scales. Different components of dyspnea will be measured.

Blood tests will be performed at different times (before dyspnea, during dyspnea, 60 and 90 min after dyspnea)

Conditions

See the medical conditions and disease areas that this research is targeting or investigating.

Healthy Volunteers

Study Design

Understand how the trial is structured, including allocation methods, masking strategies, primary purpose, and other design elements.

Allocation Method

NA

Intervention Model

SINGLE_GROUP

Primary Study Purpose

BASIC_SCIENCE

Blinding Strategy

NONE

Study Groups

Review each arm or cohort in the study, along with the interventions and objectives associated with them.

Induced dyspnea

Group Type EXPERIMENTAL

Induced dyspnea

Intervention Type OTHER

Biological samples will be assessed during and after breathing discomfort induced by laboratory models of dyspnea ("work/effort", "air hunger").

Interventions

Learn about the drugs, procedures, or behavioral strategies being tested and how they are applied within this trial.

Induced dyspnea

Biological samples will be assessed during and after breathing discomfort induced by laboratory models of dyspnea ("work/effort", "air hunger").

Intervention Type OTHER

Eligibility Criteria

Check the participation requirements, including inclusion and exclusion rules, age limits, and whether healthy volunteers are accepted.

Inclusion Criteria

* healthy volunteers

Exclusion Criteria

* pregnancy
* ongoing pain
* respiratory disease
* high levels of depression, panic disorder, or other significant mental health problems
* not fluent in french

Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes