Creation of a Biospecimen Repository From Patients With Interstitial Lung Diseases (ILD)

NCT ID: NCT03478826

Last Updated: 2025-04-27

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

RECRUITING

Total Enrollment

635 participants

Study Classification

OBSERVATIONAL

Study Start Date

2018-08-01

Study Completion Date

2028-01-31

Brief Summary

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To develop a repository of blood samples from patients with ILD to support future studies into the development of such biomarkers. Patients with pneumonia and healthy patients will also be recruited as a control group.

Detailed Description

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The proposed biospecimen repository would be derived from patients diagnosed with ILD. This is to include 500 patients in the repository, with each patient contributing one blood sample. Patients with pneumonia and healthy patients will also be recruited as a control group.

Conditions

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Interstitial Lung Disease

Study Design

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Observational Model Type

OTHER

Study Time Perspective

RETROSPECTIVE

Study Groups

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ILD

250 patients (male and females \>18 years of age) with the diagnosis of fibrotic DILD (IPF (n=100), fibrotic NSIP (n=50), chronic hypersensitivity pneumonia (n=20), sarcoidosis(n=50), progressive rheumatoid lung disease (n=10) and scleroderma lung disease (n=20), 10 patients with other fibrosing disease (fibrosing mediastinitis), and 50 patients with lymphangioleiomyomatosis.

ILD

Intervention Type OTHER

100 cc of blood collected from a total of 250 ILD patients. This includes IPF (n=100), fibrotic NSIP (n=50), chronic hypersensitivity pneumonia (n=20), sarcoidosis(n=50), progressive rheumatoid lung disease (n=10) and scleroderma lung disease (n=20)), 10 patients with other fibrosing disease (fibrosing mediastinitis), and 50 patients with lymphangioleiomyomatosis

Healthy

100 healthy participants as a control group.

Healthy

Intervention Type OTHER

100 cc of blood collected from a total of 25 healthy volunteers in order to compare with the ILD participants.

Pneumonia

25 patients with pneumonia as a control group.

Pneumonia

Intervention Type OTHER

100 cc of blood collected from a total of 100 participants with a diagnosis of pneumonia in order to compare with the ILD participants.

Interventions

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ILD

100 cc of blood collected from a total of 250 ILD patients. This includes IPF (n=100), fibrotic NSIP (n=50), chronic hypersensitivity pneumonia (n=20), sarcoidosis(n=50), progressive rheumatoid lung disease (n=10) and scleroderma lung disease (n=20)), 10 patients with other fibrosing disease (fibrosing mediastinitis), and 50 patients with lymphangioleiomyomatosis

Intervention Type OTHER

Healthy

100 cc of blood collected from a total of 25 healthy volunteers in order to compare with the ILD participants.

Intervention Type OTHER

Pneumonia

100 cc of blood collected from a total of 100 participants with a diagnosis of pneumonia in order to compare with the ILD participants.

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* Patients with a diagnosis of ILD or any fibrotic disease of the lung or a diagnosis of pneumonia
* Patients willing to provide written informed consent

Exclusion Criteria

* Unwillingness/unable to give blood samples
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Mayo Clinic

OTHER

Sponsor Role lead

Responsible Party

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Eva M. Carmona Porquera

Assistant Professor of Medicine, College of Medicine

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Eva M Carmona Porquera, MD, PhD

Role: PRINCIPAL_INVESTIGATOR

Mayo Clinic

Locations

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Mayo Clinic

Rochester, Minnesota, United States

Site Status RECRUITING

Countries

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United States

Central Contacts

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Michael Stachowitz

Role: CONTACT

507-284-4862

Facility Contacts

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Michael Stachowitz

Role: primary

507-284-4862

Other Identifiers

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17-008088

Identifier Type: -

Identifier Source: org_study_id

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