Actigraphs for Detection of Asymmetries

NCT ID: NCT03054441

Last Updated: 2018-09-14

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

106 participants

Study Classification

OBSERVATIONAL

Study Start Date

2017-01-31

Study Completion Date

2018-09-30

Brief Summary

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In hemiplegia quantitatively measurement of the asymmetry in the use of upper limbs could overcome the limitation of many outcome measures in which scores are dependent on the experience and training of the therapist. The main aim of this study was to determine the validity of Actigraph GXT3+ to measure asymmetry in the use of the two upper limbs during the Assisting Hand Assessment (AHA) in children, adolescents and young with hemiplegia aged 5-19 years, compared to age-matched typically developing subjects (TD).

Detailed Description

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This study aims to validate the use of Actigraphs as an evaluation tool of the upper limb asymmetry in children / adolescents and young adults with typical development or hemiplegia.

The validation involves two stages:

The first stage, carried out in the clinical setting, provides the use of Actigraphs (Actigraph GXT3+ and in a subgroup also FitBit) during the administration of clinical tests which are usually performed for the evaluation of the manual dominance in individuals with hemiplegia but also suitable for those with typical development.

This first phase will allow to compare the quantitative measures acquired by the actigraphs (e.g. the mean activity of each hand and the asymmetry index i.e. difference between the mean activities of the two arms) with those from clinical standardized measures.

The second phase, carried out in a non-clinical setting, provides the use of Actigraphs (Actigraph GXT3+ and in a subgroup also FitBit) in a subgroup of subject involved in the first phase for a week in order to measure the asymmetry index during the activities of daily living.

Conditions

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Hemiplegia Hemiplegic Cerebral Palsy

Study Design

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Observational Model Type

CASE_CONTROL

Study Time Perspective

PROSPECTIVE

Study Groups

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Experimental group

Children, Adolescents and Young with hemiplegia

Actigraph

Intervention Type OTHER

Actigraphs worn on wrists

Control group

Children, Adolescents and Young with typical development

Actigraph

Intervention Type OTHER

Actigraphs worn on wrists

Interventions

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Actigraph

Actigraphs worn on wrists

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* Age between 3-25 years
* Hemiplegia (experimental group) or Voluntary adhesion (control group)

Exclusion Criteria

* movement disorders
* sensory deficits
Minimum Eligible Age

3 Years

Maximum Eligible Age

25 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Scuola Superiore Sant'Anna di Pisa

OTHER

Sponsor Role collaborator

The University of Queensland

OTHER

Sponsor Role collaborator

Ministry of Health, Italy

OTHER_GOV

Sponsor Role collaborator

IRCCS Fondazione Stella Maris

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Giuseppina Sgandurra, MD, PhD

Role: PRINCIPAL_INVESTIGATOR

IRCCS Fondazione Stella Maris

Locations

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IRCCS Stella Maris Foundation

Calambrone, Pisa, Italy

Site Status

Countries

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Italy

References

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Martin JL, Hakim AD. Wrist actigraphy. Chest. 2011 Jun;139(6):1514-1527. doi: 10.1378/chest.10-1872.

Reference Type BACKGROUND
PMID: 21652563 (View on PubMed)

Nagels G, Marion P, Pickut BA, Timmermans L, De Deyn PP. Actigraphic evaluation of handedness. Electroencephalogr Clin Neurophysiol. 1996 Jun;101(3):226-32. doi: 10.1016/0924-980x(96)95566-6.

Reference Type BACKGROUND
PMID: 8647035 (View on PubMed)

Beani E, de 'Cavalieri MF, Filogna S, Barzacchi V, Cianchetti M, Maselli M, Martini G, Menici V, Prencipe G, Sicola E, Cioni G, Sgandurra G. Wearable sensors for measuring spontaneous upper limb use in children with unilateral cerebral palsy and typical development. J Neuroeng Rehabil. 2025 Apr 3;22(1):71. doi: 10.1186/s12984-025-01601-3.

Reference Type DERIVED
PMID: 40181251 (View on PubMed)

Beani E, Maselli M, Sicola E, Perazza S, Cecchi F, Dario P, Braito I, Boyd R, Cioni G, Sgandurra G. Actigraph assessment for measuring upper limb activity in unilateral cerebral palsy. J Neuroeng Rehabil. 2019 Feb 22;16(1):30. doi: 10.1186/s12984-019-0499-7.

Reference Type DERIVED
PMID: 30795810 (View on PubMed)

Other Identifiers

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GR-2011-02350053

Identifier Type: -

Identifier Source: org_study_id

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