Assessing the Effect of Different Grades of Chondromalacia on Static and Dynamic Balance Using Biodex Balance System

NCT ID: NCT07014787

Last Updated: 2025-06-11

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

RECRUITING

Total Enrollment

100 participants

Study Classification

OBSERVATIONAL

Study Start Date

2024-11-05

Study Completion Date

2025-06-15

Brief Summary

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The aim of this study is to investigate the effect of grades of chondromalacia on static and dynamic balance.

Detailed Description

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Chondromalacia patellae is a very common disorder which is characterized by softening, swelling, fraying, fissuring, and erosion of hyaline cartilage overlying the patella. Patellar chondromalacia could be observed as a cause of patellofemoral pain, as well as in patients with osteoarthritis, in patients with knee trauma, or even in asymptomatic patients.

Balance, as an essential function in human daily life and activities, can be defined as central nervous system input. Postural control can be divided into static balance and dynamic balance; static balance controls the oscillation amplitude of the body, and dynamic balance uses the body's internal and external information to analyze factors that influence the stability of interference (Such as walking, pushing and pulling),and to maintain postural control. The perfect combination of static and dynamic balance is key to normal activities of the human daily life.

100 patients, 80 with different grades of chondromalacia (Grade I, II, III, IV) with 20 participants in each group and 20 healthy participants in the control group will be recruited for the study to assess the effect of different chondromalacia grades on static and dynamic balance.

Conditions

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Chondromalacia Patella

Study Design

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Observational Model Type

OTHER

Study Time Perspective

CROSS_SECTIONAL

Study Groups

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Control Group

Control group of 20 healthy patients Normal MRI Study

No interventions assigned to this group

grade I chondromalacia.

Experimental group of 20 patients with grade I chondromalacia Softening and swelling, intact surface Nearly normal (soft indentation and/or superficial fissures and cracks) Increased T2 signal intensity of morphologically normal cartilage

No interventions assigned to this group

grade II chondromalacia

Experimental group of 20 patients with grade II chondromalacia. Fragmentation and fissuring of articular cartilage affecting an area of less than 0.5 inches Abnormal (lesions extending to \<50% of cartilage depth) A: Superficial partial-thickness cartilage defect \<50% of total articular surface thickness B: Deep partial-thickness cartilage defect \>50% of total articular surface thickness

No interventions assigned to this group

grade III chondromalacia

Experimental group of 20 patients with grade III chondromalacia Fragmentation and fissuring of articular cartilage affecting an area greater than 0.5 inches Severely abnormal (lesions extending \>50% of cartilage depth, but not through subchondral bone) Full-thickness cartilage defect

No interventions assigned to this group

grade IV chondromalacia

Experimental group of 20 patients with grade IV chondromalacia Cartilage erosion to bone Lesions involving subchondral bone

No interventions assigned to this group

Eligibility Criteria

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Inclusion Criteria

1. Age ranged from 18 to 40 years old
2. groups include both males and females
3. Patients with Grade I, II, III and IV chondromalacia: Confirmation of diagnosis by MRI
4. BMI will be ranged from 19.0 to 29.0
5. Patients with Unilateral or bilateral chondromalacia.
6. Chronic cases for more than 3 months.
7. Positive sign of Knee pain according to patellar Grind Test

Exclusion Criteria

1. patients have not undergone knee replacement.
2. patients have not done Intra-articular injection in the affected knee for the past 3 months.
3. Patients with rheumatoid arthritis or other inflammatory arthritis.
4. Patients with Vestibular disorders or neurological conditions.
Minimum Eligible Age

18 Years

Maximum Eligible Age

40 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Cairo University

OTHER

Sponsor Role lead

Responsible Party

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Selwan Khaled Mahmoud

Teaching Assistant

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Selwan Khaled Ayad, Teacher Assistant

Role: PRINCIPAL_INVESTIGATOR

Cairo University

Locations

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Faculty of physical therapy Cairo University

Giza, , Egypt

Site Status RECRUITING

Countries

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Egypt

Central Contacts

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Selwan Khaled Ayad, teacher Assistant

Role: CONTACT

+201064709563

Other Identifiers

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P.T.REC/012/005573

Identifier Type: -

Identifier Source: org_study_id

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