Cytokine Profile of the Uterine Secretome After Therapeutic Endometrial Scratching

NCT ID: NCT03042364

Last Updated: 2018-03-16

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

Get a concise snapshot of the trial, including recruitment status, study phase, enrollment targets, and key timeline milestones.

Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

150 participants

Study Classification

INTERVENTIONAL

Study Start Date

2016-10-01

Study Completion Date

2018-03-14

Brief Summary

Review the sponsor-provided synopsis that highlights what the study is about and why it is being conducted.

This study investigates the impact of endometrial scratching on endometrial secretion, when correlated to pregnancy.

Detailed Description

Dive into the extended narrative that explains the scientific background, objectives, and procedures in greater depth.

Conditions

See the medical conditions and disease areas that this research is targeting or investigating.

Infertility, Female

Study Design

Understand how the trial is structured, including allocation methods, masking strategies, primary purpose, and other design elements.

Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Randomized clinical trial
Primary Study Purpose

DIAGNOSTIC

Blinding Strategy

NONE

Study Groups

Review each arm or cohort in the study, along with the interventions and objectives associated with them.

No intervention

Standard treatment

Group Type NO_INTERVENTION

No interventions assigned to this group

Intervention

Endometrial scratching before standard treatment

Group Type EXPERIMENTAL

Pipelle de Cornier

Intervention Type OTHER

RCT with endometrial scratching prior to hormone treatment in ART. Aspiration of uterine secretion at transfer day

Interventions

Learn about the drugs, procedures, or behavioral strategies being tested and how they are applied within this trial.

Pipelle de Cornier

RCT with endometrial scratching prior to hormone treatment in ART. Aspiration of uterine secretion at transfer day

Intervention Type OTHER

Eligibility Criteria

Check the participation requirements, including inclusion and exclusion rules, age limits, and whether healthy volunteers are accepted.

Inclusion Criteria

* IVF or ICSI patients with ≥1 previous implantation failure, despite transfer of a top quality embryo or blastocyst.
* Antagonist treatment
* FSH: 2-12 IU/L
* BMI: 18-32
* Regular menstrual cycle
* Written consent

Exclusion Criteria

* Suspected intrauterine abnormalities Planned use of specialized media or AHA
Minimum Eligible Age

18 Years

Maximum Eligible Age

40 Years

Eligible Sex

FEMALE

Accepts Healthy Volunteers

No

Sponsors

Meet the organizations funding or collaborating on the study and learn about their roles.

University of Aarhus

OTHER

Sponsor Role lead

Responsible Party

Identify the individual or organization who holds primary responsibility for the study information submitted to regulators.

Responsibility Role SPONSOR

Locations

Explore where the study is taking place and check the recruitment status at each participating site.

Fertility Clinic,Aalborg University Hospital

Aalborg, , Denmark

Site Status

Fertility Clinic, Herlev Hospital

Herlev, , Denmark

Site Status

Fertility Clinic Horsens Hospital

Horsens, , Denmark

Site Status

Fertility Clinic, Skive Hospital

Skive, , Denmark

Site Status

Countries

Review the countries where the study has at least one active or historical site.

Denmark

Other Identifiers

Review additional registry numbers or institutional identifiers associated with this trial.

Miacol-2017-3H

Identifier Type: -

Identifier Source: org_study_id

More Related Trials

Additional clinical trials that may be relevant based on similarity analysis.

Endometrial Biopsy in Infertile Patients
NCT00064935 COMPLETED PHASE3
Endometrial Markers in Autoimmune Diseases
NCT03843034 ACTIVE_NOT_RECRUITING
Surgery and ART For Endometrioma
NCT03717870 NOT_YET_RECRUITING NA
Ethanol Sclerotherapy Prior to ART
NCT05962775 RECRUITING NA