Gene Expression Analysis of the Endometrium After Endometrial Biopsy in Fertile Women

NCT ID: NCT02219425

Last Updated: 2017-01-31

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

10 participants

Study Classification

INTERVENTIONAL

Study Start Date

2014-06-30

Study Completion Date

2016-08-31

Brief Summary

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The aim of this study is to evaluate the gene expression of the endometrium after an endometrial biopsy in fertile women using Next Generation Sequencing of total RNA.

Detailed Description

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An endometrial biopsy is done at cycle day LH+7 and repeated in the next cycle at cycle day LH+7.

Tissue is analysed and compared for changes in gene expression profile using Seq RNA

Conditions

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Infertility

Study Design

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Allocation Method

NA

Intervention Model

SINGLE_GROUP

Primary Study Purpose

TREATMENT

Blinding Strategy

NONE

Study Groups

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endometrial biopsy

Group Type OTHER

endometrial biopsy

Intervention Type PROCEDURE

Interventions

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endometrial biopsy

Intervention Type PROCEDURE

Other Intervention Names

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Pipelle de Cornier

Eligibility Criteria

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Inclusion Criteria

* Fertile women
* Age: 18-40 years
* BMI: 18-32
* Regular menstrual cycle
* No use of hormonal contraceptives or IUD the last 3 months

Exclusion Criteria

* Patients in need of a interpreter
* Suspected intrauterine abnormalities
* Pregnancy
Minimum Eligible Age

18 Years

Maximum Eligible Age

40 Years

Eligible Sex

FEMALE

Accepts Healthy Volunteers

Yes

Sponsors

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University of Aarhus

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Axel Forman, MD, DMsc

Role: STUDY_DIRECTOR

Departement of Gynaecology and Obstetrics, Aarhus University

Mia Steengaard Olesen, MD

Role: PRINCIPAL_INVESTIGATOR

Fertility Clinic Horsens Hospital, Aarhus University

Locations

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Fertility Clinic Horsens Hospital

Horsens, , Denmark

Site Status

Countries

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Denmark

Other Identifiers

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Miacol-2014-2H

Identifier Type: -

Identifier Source: org_study_id

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