The Effects of Secondary Smoking During One Lung Ventilation

NCT ID: NCT03006224

Last Updated: 2017-04-05

Basic Information

• Recruitment Status: COMPLETED
• Clinical Phase: NA
• Total Enrollment: 60 participants
• Study Classification: INTERVENTIONAL
• Study Start Date: 2016-12-31
• Study Completion Date: 2017-04-04

Brief Summary

Smoking and perhaps secondary smoking is associated with many perioperative and postoperative complications, especially respiratory events. Hypoxemia and airway damage can be associated with secondary smoking. The aim of study is to predict the incidence of hypoxemia and airway damage during one lung ventilation for lobectomy.

Detailed Description

Sixty patients undergoing lobectomy using one lung ventilation by double lumen tube will be included in this study. These patients will be divided into 2 groups. Groups S which will be included non smoking and secondary smoking and group SS which will be included secondary smoking ( smoking near him more than 10 cigarettes per day fore more than 5 years). Intra and postoperative arterial oxygen tension, arterial carbon dioxide tension and intraoperative peak airway pressure will be compared between the two groups.

Conditions

Smoking; Oxygen Deficiencies

Study Design

• Allocation Method: RANDOMIZED
• Intervention Model: PARALLEL
• Primary Study Purpose: OTHER
• Blinding Strategy: SINGLE

Study Groups

Group S (non smoking and secondary smoking)

I want to see the effects of seconder smoking to intraoperative arterial oxygen tension during one lung ventilation for lobectomy surgery.

Group Type: ACTIVE_COMPARATOR

One Lung Ventilation

Intervention Type: OTHER

Group SS (secondary smoking)

I want to see the effects of seconder smoking to intraoperative arterial oxygen tension during one lung ventilation for lobectomy surgery.

Group Type: ACTIVE_COMPARATOR

One Lung Ventilation

Intervention Type: OTHER

Interventions

One Lung Ventilation

Intervention Type: OTHER

Eligibility Criteria

Inclusion Criteria

• Sixty patients undergoing lobectomy using one lung ventilation by double lumen tube, ASA physical status 2 and 3.

Exclusion Criteria

• Recent chest infection, morbid obesity, renal, hepatic and ischemic hearts disease, asthma.

• Accepts Healthy Volunteers: No

Sponsors

Inonu University

OTHER

Sponsor Role: lead

Responsible Party

Ahmet Selim Ozkan

M.D.

Responsibility Role: PRINCIPAL_INVESTIGATOR

Other Identifiers

Asozkan-5

Identifier Type: -

Identifier Source: org_study_id