The Impact of the Timing of Trigger on IVF Success

NCT ID: NCT02990949

Last Updated: 2022-10-14

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

TERMINATED

Clinical Phase

NA

Total Enrollment

29 participants

Study Classification

INTERVENTIONAL

Study Start Date

2016-11-30

Study Completion Date

2022-06-15

Brief Summary

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The aim of this study is to examine the length of ovarian stimulation with the timing of trigger in an IVF cycle and its potential to impact patient outcomes.

Detailed Description

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Conditions

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Fertilization in Vitro Infertility Embryonic Development

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

NONE

Study Groups

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Testing group

Timing of trigger at end of ovarian stimulation in an IVF cycle: trigger when 2 follicles reach 18mm, OR 1 follicle reaches 18mm AND 1 follicle is between 16-18mm.

Group Type EXPERIMENTAL

Timing of trigger

Intervention Type OTHER

Control group

Group Type NO_INTERVENTION

No interventions assigned to this group

Interventions

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Timing of trigger

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* Planning to move forward with an IVF cycle
* Have met the requirements of being a patient at CCRM Colorado
* AMA: 39-44 years old And/or
* DOR: AMH \< 1 \& FSH \>10 (age independent)

Exclusion Criteria

* Contraindication for pregnancy
* Have not fulfilled requirements for IVF cycle
* Single gene couple or chromosomal rearrangement
* Severe male factor or testicular surgical sperm removal (need sufficient sperm for ICSI)
* One ovary
* Uterine anomalies
* Stage III or IV endometriosis
* Explained recurrent miscarriage
* PCO or PCOS
* Using donor oocyte or gestational carrier
Minimum Eligible Age

26 Years

Maximum Eligible Age

44 Years

Eligible Sex

FEMALE

Accepts Healthy Volunteers

Yes

Sponsors

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Fertility Laboratories Of Colorado

OTHER

Sponsor Role collaborator

Colorado Center for Reproductive Medicine

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Mandy Katz-Jaffe, PhD

Role: STUDY_DIRECTOR

CCRM, FLC

Locations

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Colorado Center for Reproductive Medicine

Lone Tree, Colorado, United States

Site Status

Countries

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United States

Other Identifiers

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20160397

Identifier Type: -

Identifier Source: org_study_id

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