Body Composition Changes During Stem Cell Transplantation: The Case Of Lymphoma Patients

NCT ID: NCT02983643

Last Updated: 2017-05-10

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Total Enrollment

105 participants

Study Classification

OBSERVATIONAL

Study Start Date

2016-01-31

Study Completion Date

2018-03-31

Brief Summary

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Skeletal Muscle Index (SMI) and Visceral Adipose Ratio (VAR) assess body composition changes and disclose malnutrition risk effectively. The aims of the study are to assess prevalence of malnutrition in patients planned for SCT, to characterize changes in body composition (SMI, total adipose tissue and VAR) that occur in the peri transplantation phase, and to identify Waist Circumference (WC) cut off points associated with the metabolic syndrome (MetSyn) in patients with B and T cell Lymphoma.

Detailed Description

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This study is a retrospective cohort study of patients having B and T cell lymphoma, who underwent SCT in the Bone Marrow Transplantation (BMT) unit at AUBMC. Consecutive patients having B and T lymphoma who underwent SCT at AUBMC will be identified by the research team and will be included as per the below inclusion and exclusion criteria. Starting from June 2016, patients who meet the inclusion criteria will be included in the study up until June 2006.

The radiologist will access the AUBMC PACS system to review PET/CT scans of the identified patients. SMI, visceral, subcutaneous and intramuscular adipose tissues will be established by assessing at the level of L3.

Conditions

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Hematopoietic Stem Cell Transplantation Malnutrition Metabolic Syndrome

Study Design

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Observational Model Type

COHORT

Study Time Perspective

RETROSPECTIVE

Eligibility Criteria

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Inclusion Criteria

* Age\>16 years
* Patients having B and T cell lymphoma who have undergone SCT at AUBMC

Exclusion Criteria

* Patients with a missing pre-SCT PET/ CT scan
* Patients with 2 missing post SCT PET / CT scan
Minimum Eligible Age

16 Years

Maximum Eligible Age

80 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Aix Marseille Université

OTHER

Sponsor Role collaborator

American University of Beirut Medical Center

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Jean El Cheikh, MD

Role: PRINCIPAL_INVESTIGATOR

AUBMC

Locations

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American University of Beirut Medical Center

Beirut, , Lebanon

Site Status RECRUITING

Countries

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Lebanon

Central Contacts

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Jean El Cheikh, MD

Role: CONTACT

9611350000 ext. 7811

Jana Jabbour, LD, MPH

Role: CONTACT

9611759668

Facility Contacts

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Jana Jabbour, LD, MPH

Role: primary

+961759668

Jean El Cheikh, MD

Role: backup

+961350000 ext. 7811

Other Identifiers

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IM.J-EC.04

Identifier Type: -

Identifier Source: org_study_id

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