Does Local Morphine Add to Local Anesthetics in Serratus Anterior Plane Block Has a System Analgesic Effect?

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

Get a concise snapshot of the trial, including recruitment status, study phase, enrollment targets, and key timeline milestones.

Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

40 participants

Study Classification

INTERVENTIONAL

Study Start Date

2016-11-30

Study Completion Date

2018-10-31

Brief Summary

Review the sponsor-provided synopsis that highlights what the study is about and why it is being conducted.

the investigators aim is to investigate and explore the effect 10 mg morphine added to local anesthetics in serratus anterior plane block for post mastectomy pain management after modified radical mastectomy in patients with breast cancer with assessment of its serum level if it will be absorbed systemically or not?

Related Clinical Trials

Explore similar clinical trials based on study characteristics and research focus.

Perioperative Analgesic Modalities for Breast Cancer Surgeries

NCT04248608

Analgesia

COMPLETED NA

Paravertebral Morphine Versus Dexmedetomidine on Acute and Chronic Postmastectomy Pain

NCT02935933

Acute Pain Chronic Pain

UNKNOWN PHASE1/PHASE2

Preoperative Erector Spinae Plane Block Versus Paravertebral Plane Block in Decreasing Post Mastectomy Pain Syndrome

NCT06036979

Chronic Postoperative Pain

NOT_YET_RECRUITING NA

Effect of Locally Administered Morphine and Bupivicaine on Acute and Chronic Postmastectomy Pain

NCT02462577

Acute Pain Chronic Pain

COMPLETED PHASE2

Efficacy of Ketamine Added to Local Anesthetic in Modified Pectoral Block for Management of Postoperative Pain

NCT02620371

Breast Cancer

COMPLETED PHASE3

Detailed Description

Dive into the extended narrative that explains the scientific background, objectives, and procedures in greater depth.

Conditions

See the medical conditions and disease areas that this research is targeting or investigating.

Postoperative Complications

Study Design

Understand how the trial is structured, including allocation methods, masking strategies, primary purpose, and other design elements.

Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

HEALTH_SERVICES_RESEARCH

Blinding Strategy

DOUBLE

Participants Investigators

Study Groups

Review each arm or cohort in the study, along with the interventions and objectives associated with them.

morphine sulphate

10mg locally morphine hydrochloride once betwwen serratus muscle and latissmus dorsi muscle

Group Type ACTIVE_COMPARATOR

Morphine Sulfate

Intervention Type DRUG

bupivacaine hydrochloride

0.25%locally bupivacaine hydrochloride once

Group Type PLACEBO_COMPARATOR

Bupivacaine Hydrochloride

Intervention Type DRUG

Interventions

Learn about the drugs, procedures, or behavioral strategies being tested and how they are applied within this trial.

Morphine Sulfate

Intervention Type DRUG

Bupivacaine Hydrochloride

Intervention Type DRUG

Other Intervention Names

Discover alternative or legacy names that may be used to describe the listed interventions across different sources.

morphine marcaine

Eligibility Criteria

Check the participation requirements, including inclusion and exclusion rules, age limits, and whether healthy volunteers are accepted.

Inclusion Criteria

* (ASA) class I-II
* body weight of 50 - 90 kg

Exclusion Criteria

* a history of bleeding diathesis,
* relevant drug allergy, opioid dependence,
* sepsis, prior surgery in the supraclavicular, infraclavicular or axillary regions, alcohol or drug abuse , patients with advanced cardiovascular disease

Minimum Eligible Age

18 Years

Maximum Eligible Age

60 Years

Eligible Sex

FEMALE

Accepts Healthy Volunteers

No