the Effect of Dexmedetomidine in Coracoid Approach Brachial Plexus Block

NCT ID: NCT02961361

Last Updated: 2023-02-15

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

PHASE4

Total Enrollment

60 participants

Study Classification

INTERVENTIONAL

Study Start Date

2016-11-12

Study Completion Date

2017-05-25

Brief Summary

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Dexmedetomidine is an α-2 adrenoreceptor agonist and has been extensively used through intravenous infusion,in order to improved the quality of block in regional anesthesia. In this prospective, randomized study, the authors focus on the effect of dexmedetomidine mixed with ropivacaine in coracoid approach brachial plexus block.

Detailed Description

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Conditions

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Injury of Upper Limb

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

DOUBLE

Participants Investigators

Study Groups

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Group Control

40 ml 0.375% ropivacaine was injected after Locating brachial plexus.

Group Type EXPERIMENTAL

ropivacaine

Intervention Type DRUG

40 ml 0.375% ropivacaine was injected after Locating brachial plexus.

Group Dexmedetomidine

40 ml 0.375% ropivacaine mixed with dexmedetomidine was injected after Locating brachial plexus.

Group Type EXPERIMENTAL

ropivacaine mixed with dexmedetomidine

Intervention Type DRUG

40 ml 0.375% ropivacaine mixed with dexmedetomidine was injected after Locating brachial plexus.

Interventions

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ropivacaine

40 ml 0.375% ropivacaine was injected after Locating brachial plexus.

Intervention Type DRUG

ropivacaine mixed with dexmedetomidine

40 ml 0.375% ropivacaine mixed with dexmedetomidine was injected after Locating brachial plexus.

Intervention Type DRUG

Eligibility Criteria

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Inclusion Criteria

1. American Society of Anesthesiologists (ASA) physical status I or II;
2. Aged 18-60 years;
3. The elbow, forearm, wrist or hand surgery

Exclusion Criteria

1. History of allergy to local anesthetics;
2. Coagulation dysfunction, neuromuscular disease or local infection;
3. The operation time is longer than the local anesthetics effective time.
Minimum Eligible Age

18 Years

Maximum Eligible Age

60 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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The First Hospital of Qinhuangdao

OTHER_GOV

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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wensheng he, MD

Role: PRINCIPAL_INVESTIGATOR

Hebei Medical University

References

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He WS, Liu Z, Wu ZY, Sun HJ, Yang XC, Wang XL. The effect of dexmedetomidine in coracoid approach brachial plexus block under dual stimulation. Medicine (Baltimore). 2018 Sep;97(39):e12240. doi: 10.1097/MD.0000000000012240.

Reference Type DERIVED
PMID: 30278495 (View on PubMed)

Other Identifiers

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Dex

Identifier Type: -

Identifier Source: org_study_id

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