Motor Recovery of the Severely Impaired Paretic Upper Limb After Mirror Therapy in Sub-acute Stroke
NCT ID: NCT02942875
Last Updated: 2016-10-24
Study Results
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Basic Information
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COMPLETED
NA
35 participants
INTERVENTIONAL
2014-09-30
2016-09-30
Brief Summary
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Detailed Description
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Stroke patients admitted to Haven of Hope Hospital will be screened according to inclusion and exclusion criteria. Eligible subjects will consent and be randomized into two groups: MT group- subjects will have daily two 30-min sessions of standardized bilateral upper limbs exercise with presence of mirror, 5 days per week for 4 consecutive weeks. During MT, a mirror is placed in the patient's mid-sagittal plane, with the reflecting surface facing the non-paretic upper limb so that the reflected image of this non-paretic limb would be perceived as the paretic upper limb. Subjects are instructed to watch at the movements of the reflected image of the non-paretic limbs and at the same time, the paretic upper limb should imitate the observed movements and be synchronized with those of the good side. Standardized bilateral upper limbs exercise (4 sets of 30 repetitions of shoulder, elbow, wrist and fingers movements) will be carried out within 30 min per session. Control group subjects will receive same daily two sessions of standardized bilateral upper limbs exercise without mirror, 5 days per week for 4 consecutive weeks. Motor functions of paretic arm of subjects measured by Fugl-Meyer Assessment (motor domain) and Wolf Motor Function Test will be assessed by independent assessor who is blinded to the group allocation of subjects before and after the 4-week intervention. Baseline comparison between the two groups was tested with independent t-test and the difference among and between groups after intervention will be tested by repeated measures ANOVA with level of significant at 0.05.
Conditions
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Study Design
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RANDOMIZED
PARALLEL
TREATMENT
SINGLE
Study Groups
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Mirror therapy group
MT group subjects will attend training sessions of bilateral upper limb exercise daily in the presence of the mirror.
mirror therapy
During MT, subjects will sit in front of a table on which a mirror will be placed vertically in the space ipsilateral to the paretic upper limb with its reflective surface facing the unaffected upper limb. The subjects are required to look at the mirror to observe the reflective image of the unaffected arm from shoulder to the hand, while it is performing certain designated movements. At the same time, the affected arm will be required to follow the unaffected arm to practice the same movements.
The upper limbs movements during the 30-min MT session are open and close of grasp; wrist flexion and extension; forearm supination and pronation; elbow flexion and extension; shoulder flexion and extension. A total of 120 repetitions for each action will be practiced.
Control therapy group
Control group subjects will undergo the same training sessions of bilateral upper limb exercise daily without mirror.
control therapy
Control group subjects undergo the same bilateral upper limbs exercise protocol without mirror
Interventions
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mirror therapy
During MT, subjects will sit in front of a table on which a mirror will be placed vertically in the space ipsilateral to the paretic upper limb with its reflective surface facing the unaffected upper limb. The subjects are required to look at the mirror to observe the reflective image of the unaffected arm from shoulder to the hand, while it is performing certain designated movements. At the same time, the affected arm will be required to follow the unaffected arm to practice the same movements.
The upper limbs movements during the 30-min MT session are open and close of grasp; wrist flexion and extension; forearm supination and pronation; elbow flexion and extension; shoulder flexion and extension. A total of 120 repetitions for each action will be practiced.
control therapy
Control group subjects undergo the same bilateral upper limbs exercise protocol without mirror
Eligibility Criteria
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Inclusion Criteria
* first stroke within the first month after stroke onset;
* has upper limb paresis contralateral to the side of cerebral hemisphere with stroke;
* Presence of active movements (at least flicker of movement in gravity free position, but not able to accomplish full range of motion against gravity) at any one joint of shoulder, elbow and hand of hemiplegic arm, and Motricity Index less than 47.
* Able to follow instructions
Exclusion Criteria
* has cognitive impairment (Mini-Mental State Examination score \< 22/30)
* has comprehension or expression aphasia;
* Presence of visuospatial neglect
* has premorbid neurological or musculoskeletal conditions that affect movements in the upper limbs
35 Years
100 Years
ALL
No
Sponsors
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The Hong Kong Polytechnic University
OTHER
Responsible Party
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CHAN Wing Chiu
Doctoral research student, Department of Rehabilitation Science, Principal Investigator
Principal Investigators
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Wing Chiu Chan, MSc
Role: PRINCIPAL_INVESTIGATOR
The Hong Kong Polytechnic University
Locations
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Haven of Hope Hospital
Tseung Kwan O, Kowloon, Hong Kong
Countries
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References
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Other Identifiers
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HSEARS20140613004
Identifier Type: -
Identifier Source: org_study_id
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