Time Prediction for Complete Recovery From Neuromuscular Blockade After Visual Recovery With Double Burst Stimulation

NCT ID: NCT02893436

Last Updated: 2016-09-08

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Total Enrollment

50 participants

Study Classification

OBSERVATIONAL

Study Start Date

2014-04-30

Study Completion Date

2016-09-30

Brief Summary

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The purpose is to calculate the time for an optimal recovery (T4/T1 \> 0.9) from the moment when 2 responses to double burst stimulation are visually identical and this for 95% of patients.

Detailed Description

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Neuromuscular monitoring is a basic monitoring for all curarised patients. Acceleromiography is used to supervise neuromuscular blockade and allow measuring in an objective and quantitative manner the curarisation level during surgery and phase of recovery from neuromuscular blockade. Various parameters are usually measured during surgery:

* T4/T1 ratio: ratio between the 4th and 1st response to "train of four" stimulation (TOF, 4 stimulations of 0.2 ms in 2 s). Neuromuscular recovery is considered appropriate if T4/T1 ratio is \> 0.9
* Double burst stimulation (DBS): 2 short tetanic stimulations separated by an interval of 750 ms.

It is known that when DBSs induce the same visual and/or tactile response, T4/T1 recovery time is \> 0.6. However, for an optimal recovery, T4/T1 ratio must be \> 0.9.

This study will analyze the interval between the moment when DBSs are visually identical and the T4/T1 ratio is \> 0.9, from anesthesia sheet of patients undergone surgery with tracheal intubation curarisation.

Results will define a minimum time to have an optimal recovery after having visually identical DBS responses.

Conditions

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Anesthesia Surgery

Study Design

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Observational Model Type

CASE_ONLY

Study Time Perspective

PROSPECTIVE

Study Groups

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Curarized patients

Surgery with tracheal intubation curarisation

Intervention Type PROCEDURE

Interventions

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Surgery with tracheal intubation curarisation

Intervention Type PROCEDURE

Eligibility Criteria

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Inclusion Criteria

* ASA score 1-3
* Needing a surgery with tracheal intubation curarisation

Exclusion Criteria

* none
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Central Hospital, Nancy, France

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Denis Schmartz

Role: PRINCIPAL_INVESTIGATOR

CHRU Nancy, France

Locations

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CHRU Nancy

Vandœuvre-lès-Nancy, , France

Site Status RECRUITING

Countries

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France

Central Contacts

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Denis Schmartz

Role: CONTACT

Other Identifiers

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PSS2014/DBSPREDICTION-SCHMARTZ

Identifier Type: -

Identifier Source: org_study_id

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