Limbal Stem Cell Deficiency of Genetic Origin: Genotype-phenotype Correlation

NCT ID: NCT02886611

Last Updated: 2025-12-03

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

RECRUITING

Total Enrollment

60 participants

Study Classification

OBSERVATIONAL

Study Start Date

2015-12-15

Study Completion Date

2026-12-31

Brief Summary

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The study aims at searching for a genotype-phenotype correlation in patients with a genetic pathology of the ocular surface, in order to identify genetic abnormalities associated with the most severe clinical situations.

Detailed Description

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Conditions

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Limbus Corneae

Study Design

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Observational Model Type

OTHER

Study Time Perspective

CROSS_SECTIONAL

Eligibility Criteria

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Inclusion Criteria

* genetic pathology of ocular surface

Exclusion Criteria

* Agonal glaucoma
* Low vision mostly related to retinal pathology
* Pregnant or breast feeding patient
Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Fondation Ophtalmologique Adolphe de Rothschild

NETWORK

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Anna GEMAHLING, MD

Role: PRINCIPAL_INVESTIGATOR

Hôpital Fondation Adolphe de Rothschild

Eric GABISON, MD

Role: PRINCIPAL_INVESTIGATOR

Hôpital Bichat (AP-HP)

Dominique BREMOND-GIGNAC, MD

Role: PRINCIPAL_INVESTIGATOR

Hopital Necker-enfants malades (AP-HP)

Locations

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Fondation Ophtalmologique Adolphe de Rothschild

Paris, , France

Site Status RECRUITING

Countries

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France

Central Contacts

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Amélie YAVCHITZ, MD, PhD

Role: CONTACT

0033148036454

Facility Contacts

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Eric GABISON, Pr

Role: primary

Other Identifiers

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EGN_2015_36

Identifier Type: -

Identifier Source: org_study_id

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