Iplasma IL6, Procalcitonin and VEGF and Dialysate Level in CAPD Patients
NCT ID: NCT02881892
Last Updated: 2016-08-29
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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COMPLETED
26 participants
OBSERVATIONAL
2012-03-31
2014-06-30
Brief Summary
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Detailed Description
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Conditions
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Study Design
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CASE_ONLY
CROSS_SECTIONAL
Interventions
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Measure plasma and dialysate level of IL-6, procalcitonin and VEGF
correlation between plasma levels, dialysate appearance rate of VEGF, inflammatory cytokines (IL- 6, procalcitonin) and PSTR, dialysis adequacy in CAPD patients.
Eligibility Criteria
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Inclusion Criteria
Exclusion Criteria
* Other infections, tuberculosis or on immunosuppressive drugs,
* Autoimmune disease,
* Cancer
* Diagnosis of permanent ultrafiltration failure .
18 Years
80 Years
ALL
No
Sponsors
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Bangkok Metropolitan Administration Medical College and Vajira Hospital
OTHER_GOV
Responsible Party
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Thananda Trakarnvanich
Associate Professor
Principal Investigators
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Thananda Trakarnvniach, M.D.
Role: PRINCIPAL_INVESTIGATOR
Department of Medicine,Vajira Hospital,Navamindradhiraj University
Locations
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Renal Unit, BMA Medical College and Vajira Hospital
Bangkok, , Thailand
Countries
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References
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Oh KH, Jung JY, Yoon MO, Song A, Lee H, Ro H, Hwang YH, Kim DK, Margetts P, Ahn C. Intra-peritoneal interleukin-6 system is a potent determinant of the baseline peritoneal solute transport in incident peritoneal dialysis patients. Nephrol Dial Transplant. 2010 May;25(5):1639-46. doi: 10.1093/ndt/gfp670. Epub 2010 Jan 8.
Alscher DM, Mettang T. Procalcitonin in peritoneal dialysis--a useful marker of inflammation? Perit Dial Int. 2005 Sep-Oct;25(5):441-4. No abstract available.
Herget-Rosenthal S, Klein T, Marggraf G, Hirsch T, Jakob HG, Philipp T, Kribben A. Modulation and source of procalcitonin in reduced renal function and renal replacement therapy. Scand J Immunol. 2005 Feb;61(2):180-6. doi: 10.1111/j.0300-9475.2005.01545.x.
Guz G, Colak B, Hizel K, Reis KA, Erten Y, Bali M, Sindel S. Procalcitonin and conventional markers of inflammation in peritoneal dialysis patients and peritonitis. Perit Dial Int. 2006 Mar-Apr;26(2):240-8.
Pecoits-Filho R, Araujo MR, Lindholm B, Stenvinkel P, Abensur H, Romao JE Jr, Marcondes M, De Oliveira AH, Noronha IL. Plasma and dialysate IL-6 and VEGF concentrations are associated with high peritoneal solute transport rate. Nephrol Dial Transplant. 2002 Aug;17(8):1480-6. doi: 10.1093/ndt/17.8.1480.
Other Identifiers
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041/57
Identifier Type: -
Identifier Source: org_study_id
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