BIA Versus Physician Adjustment in Acute Kidney Injury Patients Requiring Renal Replacement Therapy
NCT ID: NCT03916861
Last Updated: 2019-04-16
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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COMPLETED
NA
9 participants
INTERVENTIONAL
2017-10-01
2018-02-28
Brief Summary
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Detailed Description
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Volume overload and intradialytic hypotension are significant complications with increasing mortality rate in hemodialysis patients. Bioelectrical Impedance Analysis (BIA) has been used to estimate the optimum weight in chronic hemodialysis patient to prevent intradialytic hypotension.Volume assessment in acute kidney injury is also of great importance , however, there are currently few methods to obtain an accurate assessment of hydration status in this scenario. This study was designed to compare the efficacy of BIA and physician adjustment to prevent intradialytic hypotension in patients with acute kidney injury who received renal replacement therapy.
Methods
The investigators randomized 9 patients with acute kidney injury and volume overloaded who underwent acute hemodialysis for 45 sessions in Vajira hospital between October 2017 and February 2018. Volume overload was defined by BIA with value more than\>0.4. In physician adjust-group (control) estimate by physical examination and fluid balance record. Primary outcome was intradialytic hypotensive episode and secondary outcome was hemodialysis-related adverse events and other clinical outcome.
Conditions
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Study Design
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RANDOMIZED
PARALLEL
PREVENTION
NONE
Study Groups
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Bioelectrical Impedance
The first group will be monitored by Inbody S20 analysis to measure fluid status. The Bioimpedance will be measured each time prior to hemodialysis session . The value of BIA measurement of more than 0.4 will be considered as edema.
Bioelectrical Impedance Analysis
We use Inbody S20 analysis to measure fluid status before each hemodialysis session to guide fluid removal.
Physicain-guided group
The fluid monitoring will be managed by physician-adjustment by physical examination and fluid balance record . The fluid balance (FB) is the total fluid administered minus the total fluids eliminated over a period of time.
Physician-guided
This intervention used physical examination as guided to adjust fluid therapy together with the chart record of intake and output per day
Interventions
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Bioelectrical Impedance Analysis
We use Inbody S20 analysis to measure fluid status before each hemodialysis session to guide fluid removal.
Physician-guided
This intervention used physical examination as guided to adjust fluid therapy together with the chart record of intake and output per day
Other Intervention Names
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Eligibility Criteria
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Inclusion Criteria
Exclusion Criteria
* Advanced malignancy
* Kidney transplantation
* AKI from toxins
* Currently on pacemaker
* Had underlying chronic kidney disease
* Patients with severe cardiovascular disease such as congestive heart failure, valvular regurgition
18 Years
ALL
No
Sponsors
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Bangkok Metropolitan Administration Medical College and Vajira Hospital
OTHER_GOV
Responsible Party
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Thananda Trakarnvanich
Associate Professor
Principal Investigators
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Thananda Trakarnvanich
Role: PRINCIPAL_INVESTIGATOR
Vajira Hospital ,Navamindradhiraj University
Locations
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Thananda Trakarnvanich
Bangkok, Bangkok, Thailand
Countries
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Other Identifiers
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106/60
Identifier Type: -
Identifier Source: org_study_id
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