Remote Ischaemic Preconditioning to Prevent Dialysis Induced Cardiac Injury
NCT ID: NCT02630355
Last Updated: 2020-10-12
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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TERMINATED
PHASE2
32 participants
INTERVENTIONAL
2016-01-31
2018-12-31
Brief Summary
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Detailed Description
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Conditions
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Study Design
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RANDOMIZED
PARALLEL
TREATMENT
NONE
Study Groups
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Control
Inflation of blood pressure cuff in lower limb to 40mmHg for four cycles of 5 minutes inflation and then deflation
Remote Ischaemic Preconditioning
Inflation of blood pressure cuff in lower limb
Low Intensity
Inflation of blood pressure cuff in lower limb to 200mmHg for two cycles of 5 minute inflation and then deflation.
Remote Ischaemic Preconditioning
Inflation of blood pressure cuff in lower limb
Standard Intensity
Inflation of blood pressure cuff in lower limb to 200mmHg for four cycles of 5 minute inflation and then deflation.
Remote Ischaemic Preconditioning
Inflation of blood pressure cuff in lower limb
High Intensity
Inflation of blood pressure cuff in lower limb to 200mmHg for four cycles of 5 minute inflation and deflation on weekly basis for four consecutive weeks.
Remote Ischaemic Preconditioning
Inflation of blood pressure cuff in lower limb
Interventions
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Remote Ischaemic Preconditioning
Inflation of blood pressure cuff in lower limb
Eligibility Criteria
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Inclusion Criteria
2. Male and female, ageā„16 years old.
2. Exposure to haemodialysis for \<90 days prior to recruitment
3. Severe heart failure (New York Heart Association grade IV)
4. Cardiac transplant recipients
5. Mental incapacity to consent
6. Declined to participate
7. Taking cyclosporin
8. Taking ATP-sensitive potassium channel opening or blocking drugs
18 Years
ALL
No
Sponsors
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Academic Medical Organization of Southwestern Ontario
OTHER
Western University, Canada
OTHER
Responsible Party
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Christopher McIntyre
Dr.
Other Identifiers
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R-15-091
Identifier Type: -
Identifier Source: org_study_id
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