Exercise Preconditioning to Protect Against Dialysis-induced Cardiac Injury
NCT ID: NCT06735378
Last Updated: 2025-01-22
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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RECRUITING
NA
30 participants
INTERVENTIONAL
2025-01-20
2025-12-31
Brief Summary
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Detailed Description
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Conditions
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Study Design
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RANDOMIZED
CROSSOVER
PREVENTION
NONE
Study Groups
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Randomization Order 1
Participants will be randomized into one of the two groups indicating the order in which they will receive the exercise intervention.
Randomization Order 1 will receive the exercise treatment on the first day of the first week of the study. The other three days without exercise will consist of standard dialysis sessions with study procedures.
Intradialytic Cycling
The impact of interdialytic exercise on cardio protection during HD has never been studied. This approach may enhance cardiovascular benefits and overall physical fitness, thereby contributing to better health outcomes in individuals undergoing HD.
Randomization Order 2
Participants will be randomized into one of the two groups indicating the order in which they will receive the exercise intervention.
Randomization Order 2 will receive the exercise treatment on the first day of the fourth week of the study. The other three days without exercise will consist of standard dialysis sessions with study procedures.
Intradialytic Cycling
The impact of interdialytic exercise on cardio protection during HD has never been studied. This approach may enhance cardiovascular benefits and overall physical fitness, thereby contributing to better health outcomes in individuals undergoing HD.
Interventions
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Intradialytic Cycling
The impact of interdialytic exercise on cardio protection during HD has never been studied. This approach may enhance cardiovascular benefits and overall physical fitness, thereby contributing to better health outcomes in individuals undergoing HD.
Eligibility Criteria
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Inclusion Criteria
* age 18 years or older
* willing and able to provide informed consent
* assessed to be safe and able to exercise by unit HD Nephrologist
Exclusion Criteria
* over 79 years of age
* intradialytic exercise \< 3 months
* poor echogenicity
* acute coronary syndrome in the past 3 months
* unstable arrhythmia/angina
* shortness of breath at rest or with minimal activity
* symptomatic hypoglycemia (\>2x/week in the week prior to enrolment)
18 Years
79 Years
ALL
No
Sponsors
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London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
OTHER
Responsible Party
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Chris McIntyre
Nephrologist, Professor of Medicine, Medical Biophysics and Paediatrics
Principal Investigators
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Christopher McIntyre
Role: PRINCIPAL_INVESTIGATOR
London Health Sciences Centre Research Institute
Locations
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London Health Sciences Centre
London, Ontario, Canada
Countries
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Central Contacts
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Other Identifiers
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15393
Identifier Type: -
Identifier Source: org_study_id
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