Biomarkers for the Detection of Heavy Alcohol Use in Patients With and Without Liver Disease

NCT ID: NCT02873663

Last Updated: 2024-07-10

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

ACTIVE_NOT_RECRUITING

Clinical Phase

NA

Total Enrollment

140 participants

Study Classification

INTERVENTIONAL

Study Start Date

2010-12-31

Study Completion Date

2025-08-31

Brief Summary

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The investigators will test the validity of biomarkers for the detection of heavy alcohol use in patients with and without liver disease.

Detailed Description

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The investigators will test the validity of biomarkers for the detection of heavy alcohol use in patients with and without liver disease.

The investigators will test the validity of carbohydrate deficient transferrin (CDT)(using capillary zone electrophoresis) in blood and ethyl glucuronide (EtG)(using Liquid Chromatography-MS-MS) in hair in patients with heavy alcohol use, moderate alcohol use and patients who do not drink alcohol.

Conditions

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Alcohol Abuse Liver Disease

Study Design

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Allocation Method

NON_RANDOMIZED

Intervention Model

FACTORIAL

Primary Study Purpose

DIAGNOSTIC

Blinding Strategy

SINGLE

Investigators

Study Groups

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heavy drinkers

Plasma and head hair collection

Group Type EXPERIMENTAL

Plasma and head hair collection

Intervention Type PROCEDURE

Plasma and head hair collection

teetotalers

Plasma and head hair collection

Group Type EXPERIMENTAL

Plasma and head hair collection

Intervention Type PROCEDURE

Plasma and head hair collection

Interventions

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Plasma and head hair collection

Plasma and head hair collection

Intervention Type PROCEDURE

Eligibility Criteria

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Inclusion Criteria

* patients who do not drink alcohol, moderate drinkers (between 0 and 60 g a day) and patients who drink 60 or more grams alcohol a day

Exclusion Criteria

* refusal for inclusion
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Universitaire Ziekenhuizen KU Leuven

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Jef Verbeek, MD

Role: PRINCIPAL_INVESTIGATOR

Universitaire Ziekenhuizen KU Leuven

Locations

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UZ Leuven

Leuven, Vlaams Brabant, Belgium

Site Status

Countries

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Belgium

Other Identifiers

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S53031

Identifier Type: -

Identifier Source: org_study_id

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