Cough Peak Flow for Extubation Prediction

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

Get a concise snapshot of the trial, including recruitment status, study phase, enrollment targets, and key timeline milestones.

Recruitment Status

COMPLETED

Total Enrollment

92 participants

Study Classification

OBSERVATIONAL

Study Start Date

2014-11-30

Study Completion Date

2015-11-30

Brief Summary

Review the sponsor-provided synopsis that highlights what the study is about and why it is being conducted.

Successful weaning from mechanical ventilation in ICU patients depends on patient ability to breathe spontaneously and on cough efficiency. Previous studies found that cough peak flow (CPF) at 60 L/min threshold predicted extubation failure. These studies measured CPF using a dedicated flow-meter that required patient disconnection from the ventilator, limiting the generalizability of this procedure. This study aimed to predict extubation outcome in a consecutive series of patients by measuring CPF from the ventilator flow-meter. CPF measurements were done by freezing ventilator screen and scrolling the cursor to the maximal value of CPF during expiration and Tidal Volume (TV) in preceding inspiration.

The objective was to assess the performance of CPF to predict early extubation outcome.

Related Clinical Trials

Explore similar clinical trials based on study characteristics and research focus.

Assessment of Cough Strength in Patients With Tracheostomies

NCT02566512

Mechanical Ventilator Weaning

COMPLETED NA

Measuring Lung Pressures in Critically Ill Children Who Are on Mechanical Ventilation

NCT02354365

Transpulmonary Pressure Pressure.Rate Product Guide to Mechanical Ventilator Management +1 more

UNKNOWN

PHYSIOFLOW/Comparison of Cardiac Output Measurement

NCT02873494

Pediatric Disorders

COMPLETED

Does Addition of Oscillatory Positive Expiratory Pressure (OPEP) Device to a Chest Physiotherapy Program Provide Further Health Benefits in Children With Bronchiectasis?

NCT05034900

Bronchiectasis

COMPLETED NA

Study of AffloVest in At-Risk Respiratory Patients During COVID-19 Pandemic

NCT04654481

Chronic Obstructive Pulmonary Disease Chronic Cough Covid19

TERMINATED NA

Detailed Description

Dive into the extended narrative that explains the scientific background, objectives, and procedures in greater depth.

Conditions

See the medical conditions and disease areas that this research is targeting or investigating.

Extubation in ICU Patients

Study Design

Understand how the trial is structured, including allocation methods, masking strategies, primary purpose, and other design elements.

Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Eligibility Criteria

Check the participation requirements, including inclusion and exclusion rules, age limits, and whether healthy volunteers are accepted.

Inclusion Criteria

* Age \> 18 years
* Intubation \> 24h
* Eligible for scheduled weaning trial and then scheduled extubation
* Mechanical ventilation from Evita XL ventilator (Dräger, Germany)
* Patient's agreement to participate