Evaluation of Corrected Carotid Artery Flow Time as a Predictor of Fluid Responsiveness in Spontaneous Breathing Patients
NCT ID: NCT02843477
Last Updated: 2018-07-17
Study Results
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Basic Information
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COMPLETED
54 participants
OBSERVATIONAL
2016-08-09
2017-02-28
Brief Summary
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Detailed Description
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Conditions
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Study Design
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OTHER
PROSPECTIVE
Study Groups
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Fluid loading group
Spontaneously breathing patients before induction of general anesthesia who receive fluid loading
ultrasonographic measurement of corrected flow time in carotid artery
Corrected carotid artery flow time is measured using 10-5 MHz linear probe on a portable ultrasound machine. On the two-dimensional image, the optimal image of the long-axis view is obtained at the left common carotid artery. The sample volume is placed on the center of the lumen, 2 cm proximal to the bulb, and a pulsed wave Doppler examination was performed while the Doppler beams were adjusted to ensure \< 60° of angle for the best signal. Then, cardiac cycle time and carotid flow time is measured. Carotid flow time is measured between the upstroke of the flow tracing and the dicrotic notch, and it is corrected for pulse rate by dividing flow time by the square root of the cardiac cycle time to calculate corrected carotid artery flow time (flow time/√cycle time).
Interventions
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ultrasonographic measurement of corrected flow time in carotid artery
Corrected carotid artery flow time is measured using 10-5 MHz linear probe on a portable ultrasound machine. On the two-dimensional image, the optimal image of the long-axis view is obtained at the left common carotid artery. The sample volume is placed on the center of the lumen, 2 cm proximal to the bulb, and a pulsed wave Doppler examination was performed while the Doppler beams were adjusted to ensure \< 60° of angle for the best signal. Then, cardiac cycle time and carotid flow time is measured. Carotid flow time is measured between the upstroke of the flow tracing and the dicrotic notch, and it is corrected for pulse rate by dividing flow time by the square root of the cardiac cycle time to calculate corrected carotid artery flow time (flow time/√cycle time).
Eligibility Criteria
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Inclusion Criteria
Exclusion Criteria
* the presence of carotid artery stenosis \> 50%
* systolic blood pressure \> 160 mmHg
* cardiac rhythm other than sinus
* intracardiac shunt 6. valvular heart disease
* a left ventricular ejection fraction of \< 50%
* right ventricular dysfunction 9
* chronic obstructive pulmonary disease
* pulmonary hypertension
* chronic kidney disease (eGFR \< 60 mL/min/1.73m2)
* pregnancy
19 Years
80 Years
ALL
No
Sponsors
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Yonsei University
OTHER
Responsible Party
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Locations
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Department of Anesthesiology and Pain Medicine, Anesthesia and Pain Research Institue, Yonsei Universiy College of Medicine
Seoul, , South Korea
Countries
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References
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Kim DH, Shin S, Kim N, Choi T, Choi SH, Choi YS. Carotid ultrasound measurements for assessing fluid responsiveness in spontaneously breathing patients: corrected flow time and respirophasic variation in blood flow peak velocity. Br J Anaesth. 2018 Sep;121(3):541-549. doi: 10.1016/j.bja.2017.12.047. Epub 2018 Apr 12.
Other Identifiers
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4-2016-0426
Identifier Type: -
Identifier Source: org_study_id
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