Cohort Study to Assess Impact of Chemotherapy Plus Bevacizumab on Health Related Quality of Life in First Line Metastatic Colorectal Cancer

NCT ID: NCT02842294

Last Updated: 2016-07-22

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Total Enrollment

320 participants

Study Classification

OBSERVATIONAL

Study Start Date

2013-05-31

Study Completion Date

2018-02-28

Brief Summary

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The primary aim of this french multicenter national study is to assess and compare time to quality of life score deterioration (targeted dimensions : global health, fatigue and emotional functionning of EORTC QLQC30 according to the first line chemotherapy associated with bevacizumab in metastatic colorectal patients.

Detailed Description

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Conditions

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Metastatic Colorectal Cancer Quality of Life

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Study Groups

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irinotecan based chemotherapy

patients having a 1st line doublet chemotherapy including irinotecan

Bevacizumab

Intervention Type DRUG

oxaliplatin based chemotherapy

patients having a 1st line doublet chemotherapy including oxaliplatin

Bevacizumab

Intervention Type DRUG

triplet chemotherapy

patient having a 1st line triplet chemotherapy including oxaliplatin / irinotecan this cohort was added while primary objective was to compare doublet chemotherapy

Bevacizumab

Intervention Type DRUG

Interventions

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Bevacizumab

Intervention Type DRUG

Eligibility Criteria

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Inclusion Criteria

* age\> 18years
* metastatic colorectal cancer (non resectable)
* 1st chemotherapy including bevacizuman

Exclusion Criteria

* treatment contre-indication
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Centre Hospitalier Universitaire de Besancon

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Franck Bonnetain, PhD

Role: STUDY_DIRECTOR

University Hospital of Besancon

Locations

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CHRU Besançon

Besançon, Franche Comté, France

Site Status RECRUITING

Countries

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France

Central Contacts

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Marion Jacquin, Msc

Role: CONTACT

0033370632171

Ikram El SaaD, Msc

Role: CONTACT

0033370632181

Facility Contacts

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ikram es saad, msc

Role: primary

0370632181 ext. 0033

Related Links

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Other Identifiers

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P/2012/151

Identifier Type: -

Identifier Source: org_study_id

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