Postoperative Cognitive Dysfunction After Propofol Anesthesia for Noncardiac Surgery
NCT ID: NCT02841423
Last Updated: 2016-08-05
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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UNKNOWN
NA
204 participants
INTERVENTIONAL
2013-02-28
2018-02-28
Brief Summary
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Therefore,this study was designed to assess POCD after closed-loop coadministration of propofol and remifentanil guided by bispectral index in comparison to intravenous anesthesia in elderly patients undergoing major noncardiac surgery. Methods: After approval of the local ethical committee was obtained, 204 patients (American Society of Anesthesiologists physical status I-III; age, \> 55 yr) undergoing surgery (duration, \> 1 h) were enrolled into this pospective randomized monocenter study. Patients received anesthesia 3 days after using a neuropsychological test battery.
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Detailed Description
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Conditions
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Study Design
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RANDOMIZED
PARALLEL
DIAGNOSTIC
NONE
Study Groups
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INTRAVENOUS ANESTHESIA
neuropsychological test battery
neuropsychological test battery
CLOSED LOOP ANESTHESIA
neuropsychological test battery
neuropsychological test battery
Interventions
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neuropsychological test battery
Eligibility Criteria
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Inclusion Criteria
* undergoing surgery (duration, \> 1 h)
Exclusion Criteria
55 Years
ALL
No
Sponsors
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Centre Hospitalier Universitaire de Besancon
OTHER
Responsible Party
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Principal Investigators
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E SAMAIN, PR
Role: PRINCIPAL_INVESTIGATOR
Centre Hospitalier Universitaire de Besancon
Locations
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Chu Besancon
Besançon, , France
Countries
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Central Contacts
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E SAMAIN, PR
Role: CONTACT
Facility Contacts
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E SAMAIN, PR
Role: primary
References
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Besch G, Vettoretti L, Claveau M, Boichut N, Mahr N, Bouhake Y, Liu N, Chazot T, Samain E, Pili-Floury S. Early post-operative cognitive dysfunction after closed-loop versus manual target controlled-infusion of propofol and remifentanil in patients undergoing elective major non-cardiac surgery: Protocol of the randomized controlled single-blind POCD-ELA trial. Medicine (Baltimore). 2018 Oct;97(40):e12558. doi: 10.1097/MD.0000000000012558.
Other Identifiers
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API/2013/44
Identifier Type: -
Identifier Source: org_study_id
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