Cortical Activation in Individuals With Finger Amputation During Mirror Versus Imagery Treatment

NCT ID: NCT02838485

Last Updated: 2016-07-20

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Clinical Phase

NA

Total Enrollment

20 participants

Study Classification

INTERVENTIONAL

Study Start Date

2016-08-31

Brief Summary

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Goals : ( a) to examine differences in cortical activity during hand movements with a mirror compared to imagery of the same movements, and (b) to examine correlation between cortical activity during imagery or mirror treatment and the pain and performance measures in finger amputees.

A cross-sectional study of 20 subjects in a Functional Magnetic Resonance Imaging (fMRI) preforming mirror therapy hand movement and imagery hand movement. Also, Visual Analogue Scale for pain and the Disability of the Arm, Shoulder and Hand (DASH) questionnaire and Jebsen Taylor Hand Function Test will be used.

Detailed Description

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Goals : ( a) to examine differences in cortical activity during hand movements with a mirror compared to imagery of the same movements, and (b) to examine correlation between cortical activity during imagery or mirror treatment and the pain and performance measures in finger amputees.

A cross-sectional one-meeting study of 20 subjects (finger amputees) in a Functional Magnetic Resonance Imaging (fMRI) preforming mirror therapy hand movement and imagery hand movement. Also, Visual Analogue Scale for pain and the Disability of the Arm, Shoulder and Hand (DASH) questionnaire and Jebsen Taylor Hand Function Test will be used.

Conditions

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Amputees

Study Design

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Allocation Method

NA

Intervention Model

SINGLE_GROUP

Primary Study Purpose

BASIC_SCIENCE

Blinding Strategy

NONE

Study Groups

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Amputees

The subjects will receive both mirror and imagery treatments in a cross-over design.

Group Type EXPERIMENTAL

Mirror

Intervention Type OTHER

The healthy hand will be mirrored and the amputated hand unseen by the subject while performing hand movements.

Imagery

Intervention Type OTHER

The subject will be asked to imagine performing hand movements.

Interventions

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Mirror

The healthy hand will be mirrored and the amputated hand unseen by the subject while performing hand movements.

Intervention Type OTHER

Imagery

The subject will be asked to imagine performing hand movements.

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* Following unilateral traumatic finger or fingers amputation (1 to 3 fingers)
* Self-reported limited functionality, sensory disorder or pain

Exclusion Criteria

* Are not comparable with MRI restrictions
* Chronic pain disease
* Psychiatric condition
Minimum Eligible Age

18 Years

Maximum Eligible Age

67 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Tel Aviv University

OTHER

Sponsor Role collaborator

Hadassah Medical Organization

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Locations

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Hadassah Medical Center

Jerusalem, , Israel

Site Status

Countries

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Israel

Central Contacts

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Isabella Schwartz, MD

Role: CONTACT

Hadas Lemberg, PhD

Role: CONTACT

00 972 2 6777572

References

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Chan BL, Witt R, Charrow AP, Magee A, Howard R, Pasquina PF, Heilman KM, Tsao JW. Mirror therapy for phantom limb pain. N Engl J Med. 2007 Nov 22;357(21):2206-7. doi: 10.1056/NEJMc071927. No abstract available.

Reference Type BACKGROUND
PMID: 18032777 (View on PubMed)

Deconinck FJ, Smorenburg AR, Benham A, Ledebt A, Feltham MG, Savelsbergh GJ. Reflections on mirror therapy: a systematic review of the effect of mirror visual feedback on the brain. Neurorehabil Neural Repair. 2015 May;29(4):349-61. doi: 10.1177/1545968314546134. Epub 2014 Aug 26.

Reference Type BACKGROUND
PMID: 25160567 (View on PubMed)

Other Identifiers

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Mirror- HMO-CTIL

Identifier Type: -

Identifier Source: org_study_id

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