Ultrasound-guided Femoral Vein Accessibility, Safety and Time for Atrial Fibrillation Treatment

NCT ID: NCT02834221

Last Updated: 2017-06-07

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

320 participants

Study Classification

INTERVENTIONAL

Study Start Date

2016-06-30

Study Completion Date

2016-11-30

Brief Summary

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This study is designed to evaluate the use of real-time ultrasound-guided femoral venipuncture during pulmonary vein isolation for treating atrial fibrillation .

Detailed Description

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The number of pulmonary vein isolation (PVI) therapy for atrial fibrillation (AF) is increasing. Multiple femoral vein cannulation is mandatory for this procedure. There are mainly two methods to cannulate the femoral vein; by anatomical landmark or by under real-time ultrasound-guided. As high anticoagulant level is required for the procedure, there are 0-13% of vascular access complication.

Real-time ultrasound assistance for central venous catheter cannulation has been proven to reduce complications. In the field of AF treatment, multiple femoral vein cannulation is required as many catheter is required for the procedure and larger sheaths are inserted with a high anticoagulant level during the procedure. In this setting, the use of ultrasound use is not well studied.

The current study is to confirm whether real time ultrasound-guided femoral vein cannulation for PVI can prevent complications, reduce puncture time, puncture attempts and accidental artery puncture compared to conventional anatomical approach. Two seethes for each femoral vein is going to be cannulated.

The study design is a multicenter prospective randomized trial to compare the above safety and efficacy by using the ultrasound-guided and anatomical landmark approach. Also time for cannulation, number of puncture attempts, need of X-ray for cannulation will be analyzed in the setting of patient factors including age, body mass index and sex.

Conditions

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Atrial Fibrillation Peripheral Vascular Disease Vascular Access Complications

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

PREVENTION

Blinding Strategy

SINGLE

Outcome Assessors

Study Groups

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Real-time ultrasound-guided puncture

Cannulate each femoral veins with two wires with real-time ultrasound-guided method.

Group Type EXPERIMENTAL

Real-time ultrasound-guided puncture

Intervention Type DEVICE

A 7 megahertz ultrasound linear probe will be used.

Anatomical landmark guided puncture

Cannulate each femoral veins with two wires with the anatomical landmark guided method.

Group Type OTHER

Anatomical landmark guided puncture

Intervention Type OTHER

Anatomical landmark puncture

Interventions

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Real-time ultrasound-guided puncture

A 7 megahertz ultrasound linear probe will be used.

Intervention Type DEVICE

Anatomical landmark guided puncture

Anatomical landmark puncture

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* Patients undergoing pulmonary vein isolation with radiofrequency catheter ablation for atrial fibrillation treatment.

Exclusion Criteria

* Patients with prior known vascular access problems or priory included to the current study.
Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Kenichiro Yamagata

OTHER_GOV

Sponsor Role lead

Responsible Party

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Kenichiro Yamagata

MD, PhD

Responsibility Role SPONSOR_INVESTIGATOR

Principal Investigators

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Joseph Kautzner, MD, PhD

Role: STUDY_DIRECTOR

Institute for Clinical and Experimental Medicine

Locations

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Regional Hospital Liberec

Liberec, , Czechia

Site Status

Institute for Clinical and Experimental Medicine

Prague, , Czechia

Site Status

Ústřední vojenská nemocnice

Prague, , Czechia

Site Status

Kawakita General Hospital

Tokyo, , Japan

Site Status

Countries

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Czechia Japan

References

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Yamagata K, Wichterle D, Roubicek T, Jarkovsky P, Sato Y, Kogure T, Peichl P, Konecny P, Jansova H, Kucera P, Aldhoon B, Cihak R, Sugimura Y, Kautzner J. Ultrasound-guided versus conventional femoral venipuncture for catheter ablation of atrial fibrillation: a multicentre randomized efficacy and safety trial (ULTRA-FAST trial). Europace. 2018 Jul 1;20(7):1107-1114. doi: 10.1093/europace/eux175.

Reference Type RESULT
PMID: 28575490 (View on PubMed)

Other Identifiers

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ULTRA-FAST

Identifier Type: -

Identifier Source: org_study_id

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