Impact of Child Positioning on Pain During a Lumbar Puncture

NCT ID: NCT02834156

Last Updated: 2018-03-12

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

28 participants

Study Classification

INTERVENTIONAL

Study Start Date

2015-06-30

Study Completion Date

2017-08-23

Brief Summary

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This protocol is a pilot study on standard care. The main goal is to assess the impact of positioning on lumbar puncture process especially on pain sensitivity in children.

It's a prospective, monocentric, randomized, open-label, cross-over study. Inclusion period is one year, and number of inclusions forecasted is about 30. Each patient will have one LP in a seated position and one in a lying position.

Detailed Description

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In Pediatric Oncology Hematology, invasive procedures such lumbar punctures or myelograms are essential to diseases diagnosis and treatment.

In hematological malignancies, lumbar punctures are particularly frequent as the therapy processes. Despite a good analgesia, this repeated procedure can generate pain, anxiety, apprehension leading to an increasing difficulty in the procedure realization.

Two positions are possible to carry out lumbar puncture: seated or lying position.

The main goal of this study is to assess the impact of the child positioning during the lumbar puncture process in term of pain, anxiety and stress.

This study is a prospective, monocentric, randomized, open-label, cross-over study. Inclusion period is 1 year, 30 patients will be included from 2 to 18 years old.

Each patient will have 2 LP one in seated and one in lying position in a specific order determined by randomization.

All data regarding pain and anxiety will be collected the day of LP. Patients will be re contacted 48 hours and 15 days after LP procedure in order to evaluate complications such post-lumbar puncture syndrome or hematoma. The main analysis will be done on intent-to-treat-analysis basis and will compare pain intensity between the two groups.

Conditions

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Hematological Malignancies

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

CROSSOVER

Primary Study Purpose

OTHER

Blinding Strategy

NONE

Study Groups

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LP in a seated position then LP in a lying position

Patients will have first a lumbar puncture (LP) in a seated position then a LP in a lying position

Group Type OTHER

LP in a seated position then LP in a lying position

Intervention Type OTHER

LP in a lying position then LP in a seated position

Patients will have first a lumbar puncture (LP) in a lying position then a LP in a seated position

Group Type OTHER

LP in a lying position then LP in a seated position

Intervention Type OTHER

Interventions

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LP in a seated position then LP in a lying position

Intervention Type OTHER

LP in a lying position then LP in a seated position

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* Age between 2 and 18 years old
* Patients requiring at least 2 therapeutic lumbar punctures
* Patients able to receive analgesic procedure according to 20005 good practices recommendation
* Presence of one parent during LP procedure
* Child able to use assessment scales
* LP realized with a 20 G needle
* Platelets \> 50000
* Child with prior clinical examination
* Affiliated to a health care insurance regimen

Exclusion Criteria

* Seated or lying position impossible
* Lumbar puncture contraindication
* Patient or parent opposition to second LP realization in the required position
* Clotting trouble on LP day not allowing the LP procedure
Minimum Eligible Age

2 Years

Maximum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Centre Hospitalier Universitaire de Nice

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Locations

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CHU de Nice

Nice, , France

Site Status

Countries

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France

Other Identifiers

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15-PP-05

Identifier Type: -

Identifier Source: org_study_id

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