Microtransplantation in Older Patients With Acute Myeloid Leukemia

NCT ID: NCT02831192

Last Updated: 2016-07-13

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

PHASE2

Total Enrollment

150 participants

Study Classification

INTERVENTIONAL

Study Start Date

2006-05-31

Study Completion Date

2015-07-31

Brief Summary

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The purpose of this study is to see whether HLA-mismatched donor cells infusion with chemotherapy (microtransplantation,MST) could increase complete remission (CR) and improve survival in older patients with acute myeloid leukemia (AML),the investigators conducted a prospective, multicenter clinical trial of HLA-mismatched MST to estimate outcomes and toxicities.

Detailed Description

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Conditions

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Acute Myeloid Leukemia

Study Design

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Allocation Method

NA

Intervention Model

SINGLE_GROUP

Primary Study Purpose

TREATMENT

Blinding Strategy

NONE

Study Groups

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MST(microtransplantation)

Group Type EXPERIMENTAL

microtransplantation

Intervention Type BIOLOGICAL

HLA mismatched donor mobilized prepheral stem cell infusion

Interventions

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microtransplantation

HLA mismatched donor mobilized prepheral stem cell infusion

Intervention Type BIOLOGICAL

Eligibility Criteria

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Inclusion Criteria

* de novo acute myeloid leukemia
* age 60-90
* have HLA mismatched donor

Exclusion Criteria

* have no suitable donor or donor refused
* patient refused to accept donor cells
Minimum Eligible Age

60 Years

Maximum Eligible Age

90 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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The Affiliated Hospital of the Chinese Academy of Military Medical Sciences

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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AI huisheng, MD

Role: STUDY_CHAIR

Affiliated Hospital of Academy of Military Medical Sciences

Locations

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Affiliated Hospital of Academy of Military Medical Sciences ,

Beijing, Beijing Municipality, China

Site Status

Countries

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China

Other Identifiers

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EAML-MST

Identifier Type: -

Identifier Source: org_study_id

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