Study on Cardiovascular Health, Nutrition and Frailty in Older Adults in Spain

NCT ID: NCT02804672

Last Updated: 2019-05-01

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

1566 participants

Study Classification

OBSERVATIONAL

Study Start Date

2008-03-31

Study Completion Date

2017-06-30

Brief Summary

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The purpose of this study is to examine the association between ideal cardiovascular health, diet and other lifestyles, biological risk factors, either well-established or emergent, and the risk of frailty in older adults, throughout different waves (2008-10, 2012 and 2015 -16).

Detailed Description

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Conditions

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Physical Disability Cardiovascular Risk Factors

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Eligibility Criteria

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Inclusion Criteria

* Non-institutionalized Spanish resident
* 60 years and over

Exclusion Criteria

* None
Minimum Eligible Age

60 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Universidad Autonoma de Madrid

OTHER

Sponsor Role lead

Responsible Party

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Fernando Rodríguez-Artalejo

Professor of Preventive Medicine and Public Health

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Fernando Rodríguez-Artalejo, MD, PhD

Role: PRINCIPAL_INVESTIGATOR

Department of Preventive Medicine and Public Health, Universidad Autónoma de Madrid

Jose R Banegas, MD, PhD

Role: PRINCIPAL_INVESTIGATOR

Department of Preventive Medicine and Public Health, Universidad Autónoma de Madrid

Locations

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Department of Preventive Medicine and Public Health, Universidad Autónoma de Madrid

Madrid, , Spain

Site Status

Countries

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Spain

References

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Banegas JR, de la Cruz JJ, Graciani A, Lopez-Garcia E, Gijon-Conde T, Ruilope LM, Rodriguez-Artalejo F. Impact of Ambulatory Blood Pressure Monitoring on Reclassification of Hypertension Prevalence and Control in Older People in Spain. J Clin Hypertens (Greenwich). 2015 Jun;17(6):453-61. doi: 10.1111/jch.12525. Epub 2015 Mar 16.

Reference Type RESULT
PMID: 25779903 (View on PubMed)

Garcia-Esquinas E, Graciani A, Guallar-Castillon P, Lopez-Garcia E, Rodriguez-Manas L, Rodriguez-Artalejo F. Diabetes and risk of frailty and its potential mechanisms: a prospective cohort study of older adults. J Am Med Dir Assoc. 2015 Sep 1;16(9):748-54. doi: 10.1016/j.jamda.2015.04.008. Epub 2015 May 16.

Reference Type RESULT
PMID: 25986874 (View on PubMed)

Lana A, Rodriguez-Artalejo F, Lopez-Garcia E. Dairy Consumption and Risk of Frailty in Older Adults: A Prospective Cohort Study. J Am Geriatr Soc. 2015 Sep;63(9):1852-60. doi: 10.1111/jgs.13626. Epub 2015 Aug 27.

Reference Type RESULT
PMID: 26311353 (View on PubMed)

Sandoval-Insausti H, Perez-Tasigchana RF, Lopez-Garcia E, Garcia-Esquinas E, Rodriguez-Artalejo F, Guallar-Castillon P. Macronutrients Intake and Incident Frailty in Older Adults: A Prospective Cohort Study. J Gerontol A Biol Sci Med Sci. 2016 Oct;71(10):1329-34. doi: 10.1093/gerona/glw033. Epub 2016 Mar 4.

Reference Type RESULT
PMID: 26946103 (View on PubMed)

Graciani A, Garcia-Esquinas E, Lopez-Garcia E, Banegas JR, Rodriguez-Artalejo F. Ideal Cardiovascular Health and Risk of Frailty in Older Adults. Circ Cardiovasc Qual Outcomes. 2016 May;9(3):239-45. doi: 10.1161/CIRCOUTCOMES.115.002294. Epub 2016 May 10.

Reference Type RESULT
PMID: 27166207 (View on PubMed)

Vazquez-Fernandez A, Caballero FF, Yevenes-Briones H, Struijk EA, Baylin A, Fung TT, Lopez-Garcia E. Plant and Animal Protein Intake and Transitions From Multimorbidity to Frailty and Mortality in Older Adults. J Cachexia Sarcopenia Muscle. 2025 Feb;16(1):e13729. doi: 10.1002/jcsm.13729.

Reference Type DERIVED
PMID: 39971333 (View on PubMed)

Marcos-Delgado A, Yevenes-Briones H, Fernandez-Villa T, Martin-Sanchez V, Guallar-Castillon P, Rodriguez-Artalejo F, Lopez-Garcia E. Association between diet quality and malnutrition: pooled results from two population-based studies in older adults. BMC Geriatr. 2024 May 10;24(1):417. doi: 10.1186/s12877-024-04984-5.

Reference Type DERIVED
PMID: 38730363 (View on PubMed)

Delgado-Velandia M, Maroto-Rodriguez J, Ortola R, Garcia-Esquinas E, Rodriguez-Artalejo F, Sotos-Prieto M. Plant-Based Diets and All-cause and Cardiovascular Mortality in a Nationwide Cohort in Spain: The ENRICA Study. Mayo Clin Proc. 2022 Nov;97(11):2005-2015. doi: 10.1016/j.mayocp.2022.06.008.

Reference Type DERIVED
PMID: 36333014 (View on PubMed)

Sotos-Prieto M, Ortola R, Lopez-Garcia E, Rodriguez-Artalejo F, Garcia-Esquinas E. Adherence to the Mediterranean Diet and Physical Resilience in Older Adults: The Seniors-ENRICA Cohort. J Gerontol A Biol Sci Med Sci. 2021 Feb 25;76(3):505-512. doi: 10.1093/gerona/glaa277.

Reference Type DERIVED
PMID: 33152061 (View on PubMed)

Garcia-Esquinas E, Rodriguez-Sanchez I, Ortola R, Lopez-Garcia E, Caballero FF, Rodriguez-Manas L, Banegas JR, Rodriguez-Artalejo F. Gender Differences in Pain Risk in Old Age: Magnitude and Contributors. Mayo Clin Proc. 2019 Sep;94(9):1707-1717. doi: 10.1016/j.mayocp.2019.03.034.

Reference Type DERIVED
PMID: 31486377 (View on PubMed)

Sandoval-Insausti H, Blanco-Rojo R, Graciani A, Lopez-Garcia E, Moreno-Franco B, Laclaustra M, Donat-Vargas C, Ordovas JM, Rodriguez-Artalejo F, Guallar-Castillon P. Ultra-processed Food Consumption and Incident Frailty: A Prospective Cohort Study of Older Adults. J Gerontol A Biol Sci Med Sci. 2020 May 22;75(6):1126-1133. doi: 10.1093/gerona/glz140.

Reference Type DERIVED
PMID: 31132092 (View on PubMed)

Other Identifiers

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Seniors-ENRICA

Identifier Type: -

Identifier Source: org_study_id

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