The Impact of the Opiate Antagonist Naltrexone on the Emotional Valence of Dreams

NCT ID: NCT02792140

Last Updated: 2017-04-05

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

PHASE4

Total Enrollment

32 participants

Study Classification

INTERVENTIONAL

Study Start Date

2016-03-31

Study Completion Date

2016-11-30

Brief Summary

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In this study, the investigators pose the question which influence the opioid circuit has on positive valent situations in dreams.

Detailed Description

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Conditions

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Neuroscience of Dreaming, Healthy

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

CROSSOVER

Primary Study Purpose

BASIC_SCIENCE

Blinding Strategy

DOUBLE

Participants Investigators

Study Groups

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Baseline

reporting of dreams

Group Type NO_INTERVENTION

No interventions assigned to this group

Naltrexone

daily administration of 50mg Naltrexone, reporting of dreams

Group Type EXPERIMENTAL

Naltrexone

Intervention Type DRUG

one week

Placebo

daily administration of Placebo, reporting of dreams

Group Type PLACEBO_COMPARATOR

Placebo

Intervention Type OTHER

one week

Interventions

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Naltrexone

one week

Intervention Type DRUG

Placebo

one week

Intervention Type OTHER

Other Intervention Names

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Naltrexin Placebo Pills

Eligibility Criteria

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Inclusion Criteria

* Written informed consent
* Healthiness
* Good capacity of remembering dreams
* No opiate consumption

Exclusion Criteria

* Simultaneous participation in other studies
* Addictive disorder
* Abnormal liver function
* Abnormal kidney function
* Hypersensitivity to active ingredient or pharmaceutical additives
* Hereditary galactose intolerance
* Lactase deficiency
* Glucose-galactose malabsorption
* Intake of opioid medication
Minimum Eligible Age

20 Years

Maximum Eligible Age

40 Years

Eligible Sex

MALE

Accepts Healthy Volunteers

Yes

Sponsors

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Insel Gruppe AG, University Hospital Bern

OTHER

Sponsor Role collaborator

University of Bern

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Fred Mast, Prof. Dr. phil.

Role: STUDY_DIRECTOR

Head of Cognitive Psychology, Perception and Research Methods, Dean Human Sciences Faculty, Ordinarius, University of Bern

Claudio L. Bassetti, Prof. Dr. med.

Role: PRINCIPAL_INVESTIGATOR

Chairman and Head, Department of Neurology Inselspital, Bern University Hospital

Locations

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University of Bern

Bern, Canton of Bern, Switzerland

Site Status

Countries

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Switzerland

Other Identifiers

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2015DR2186

Identifier Type: -

Identifier Source: org_study_id

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