Study to Determine Whether Ramelteon Helps People With REM Sleep Behavior Disorder

NCT ID: NCT01401413

Last Updated: 2011-07-25

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

PHASE4

Total Enrollment

20 participants

Study Classification

INTERVENTIONAL

Study Start Date

2008-01-31

Study Completion Date

2010-09-30

Brief Summary

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The purpose of this study is to determine whether the use of the drug ramelteon decreases the symptoms of REM Sleep Behavior Disorder.

Detailed Description

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This is a randomized double blind placebo controlled study to determine whether the use of ramelteon decreases symptoms of RBD. Outcome measures are determined by change in RBD polysomnographic score and assessment scores on the RBD symptom questionnaire and sleep diary.

Conditions

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REM Sleep Behavior Disorder

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

DOUBLE

Participants Investigators

Study Groups

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1

placebo control nightly

Group Type PLACEBO_COMPARATOR

placebo

Intervention Type DRUG

placebo control i pill nightly for 30 nights

2

8 mg ramelteon nightly

Group Type ACTIVE_COMPARATOR

ramelteon

Intervention Type DRUG

8 mg nightly for 30 nights

Interventions

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ramelteon

8 mg nightly for 30 nights

Intervention Type DRUG

placebo

placebo control i pill nightly for 30 nights

Intervention Type DRUG

Other Intervention Names

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rozerem

Eligibility Criteria

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Inclusion Criteria

* Meets criteria for RBD as determined by screening PSG's
* steady bed partner for completion of RBD questionnaire

Exclusion Criteria

* Hepatic impairment
* RBD associated with narcolepsy
* use of fluvoxamine, rifampin, fluconazole or ketoconazole
* current alcohol or drug abuse
Minimum Eligible Age

18 Years

Maximum Eligible Age

80 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Sleep Medicine Centers of WNY

OTHER

Sponsor Role lead

Responsible Party

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President

Principal Investigators

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Daniel I Rifkin, MD

Role: PRINCIPAL_INVESTIGATOR

Sleep medicine Centers of Western New York

Locations

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Sleep Medicine Centers of WNY

West Seneca, New York, United States

Site Status

Countries

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United States

Other Identifiers

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NEU1640207B

Identifier Type: -

Identifier Source: org_study_id

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