BIO|MASTER.Ilivia Family / Plexa

NCT ID: NCT02774616

Last Updated: 2019-05-22

Study Results

Results available

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Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

292 participants

Study Classification

INTERVENTIONAL

Study Start Date

2016-06-30

Study Completion Date

2018-03-31

Brief Summary

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Post-Market Clinical Follow-up of the new Ilivia ICD Family and the new Plexa right ventricular lead to fulfill requirements by the notified body and to support regulatory approval outside of the CE region

Detailed Description

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Conditions

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Heart Failure Tachyarrhythmia

Study Design

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Allocation Method

NON_RANDOMIZED

Intervention Model

SINGLE_GROUP

Primary Study Purpose

OTHER

Blinding Strategy

NONE

Study Groups

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Ilivia ICD Family

Implant of the new Ilivia ICD Family. Device measurements, pre-defined programming and Adverse Event Reporting

Group Type OTHER

Ilivia ICD Family

Intervention Type DEVICE

pre-defined device programming, measurements and follow-up schedule

Plexa ICD lead

Implant of the new Plexa ICD lead. Device measurements and Adverse Event Reporting

Group Type OTHER

Plexa ICD lead

Intervention Type DEVICE

predefined follow-up schedule

Ilivia ICD and Plexa lead

Implant of the new Ilivia ICD Family and the new Plexa lead. Device measurements, pre-defined programming and Adverse Event Reporting

Group Type OTHER

Ilivia ICD Family

Intervention Type DEVICE

pre-defined device programming, measurements and follow-up schedule

Plexa ICD lead

Intervention Type DEVICE

predefined follow-up schedule

Interventions

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Ilivia ICD Family

pre-defined device programming, measurements and follow-up schedule

Intervention Type DEVICE

Plexa ICD lead

predefined follow-up schedule

Intervention Type DEVICE

Eligibility Criteria

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Inclusion Criteria

* Standard indication for ICD or CRT-D therapy according to clinical practice
* De novo implantation or upgrade/exchange (group A only) from existing ICD, CRT-D or pacemaker implant
* Patient is able to understand the nature of the clinical investigation and provides written informed consent
* Patient is able and willing to complete all routine study visits at the investigational site
* Patient accepts Home Monitoring concept
* Age ≥ 18 years

Exclusion Criteria

* Contraindication to ICD or CRT-D therapy, respectively
* For CRT-D patients in group A only: physician not willing to activate MultiPole Pacing in the patient
* Cardiac surgical procedure planned within 6 months after implantation (including also interventional procedures like ablation, valve replacement etc.). Procedures to occur during or prior to implantation are not exclusionary.
* Expected to receive heart transplant or ventricular assist device within 6 months
* Life expectancy less than 6 months
* Participation in any other interventional clinical investigation
* Pregnant or breastfeeding at time of enrollment
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Biotronik SE & Co. KG

INDUSTRY

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Christian Sticherling, Prof. Dr.

Role: STUDY_CHAIR

Universitätsspital Basel

Locations

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Liverpool Hospital

Liverpool, , Australia

Site Status

Nambour General Hospital

Nambour, , Australia

Site Status

Universitätsklinikum St. Pölten

Sankt Pölten, , Austria

Site Status

Odense University Hospital

Odense, , Denmark

Site Status

CHU Brest

Brest, , France

Site Status

Hufeland Klinikum GmbH

Bad Langensalza, , Germany

Site Status

HDZ NRW Bad Oeynhausen

Bad Oeynhausen, , Germany

Site Status

Städtisches Klinikum Brandenburg GmbH

Brandenburg, , Germany

Site Status

Universitätsklinikum Erlangen

Erlangen, , Germany

Site Status

Universitätsklinikum Essen

Essen, , Germany

Site Status

Universitätsklinikum Freiburg

Freiburg im Breisgau, , Germany

Site Status

SRH Wald-Klinikum Gera GmbH

Gera, , Germany

Site Status

Westpfalz-Klinikum Kaiserslautern

Kaiserslautern, , Germany

Site Status

Hegau-Bodensee-Klinikum Singen

Singen, , Germany

Site Status

Universitätsklinikum Würzburg

Würzburg, , Germany

Site Status

Chaim Sheba Medical Center

Ramat Gan, , Israel

Site Status

Tel Aviv Sourasky Medical Center

Tel Aviv, , Israel

Site Status

Pauls Stradins Clinical University Hospital

Riga, , Latvia

Site Status

National Heart Center Singapore

Singapore, , Singapore

Site Status

Hospital de Bellvitge

Barcelona, , Spain

Site Status

Hospital de Donostia

Donostia / San Sebastian, , Spain

Site Status

Hospital Universitario Virgen de Macarena

Seville, , Spain

Site Status

Universitätsspital Basel

Basel, , Switzerland

Site Status

Inselspital Bern

Bern, , Switzerland

Site Status

Kantonspital Luzern

Lucerne, , Switzerland

Site Status

Countries

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Australia Austria Denmark France Germany Israel Latvia Singapore Spain Switzerland

Provided Documents

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Document Type: Study Protocol

View Document

Document Type: Statistical Analysis Plan

View Document

Other Identifiers

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TA111

Identifier Type: -

Identifier Source: org_study_id

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