Post Market Clinical Follow-up Study for the Pamira ICD Lead Family

NCT ID: NCT05621187

Last Updated: 2025-02-26

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

221 participants

Study Classification

INTERVENTIONAL

Study Start Date

2022-11-30

Study Completion Date

2025-01-20

Brief Summary

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Confirm clinical safety and performance of the Pamira lead to support the regulatory post market strategy in Europe and other regions and validating promotional claims by

* demonstrating clinical safety
* evaluating performance based on sensing and pacing assessment
* collecting additional data of interest to assess other aspects such as the handling and usability

Detailed Description

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Conditions

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Heart Failure Tachyarrhythmia

Study Design

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Allocation Method

NA

Intervention Model

SINGLE_GROUP

Primary Study Purpose

OTHER

Blinding Strategy

NONE

Study Groups

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All patients

Group Type OTHER

Pamira ICD lead family

Intervention Type DEVICE

Implantation, measurements and follow-up schedule

Interventions

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Pamira ICD lead family

Implantation, measurements and follow-up schedule

Intervention Type DEVICE

Eligibility Criteria

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Inclusion Criteria

* Standard indication for ICD or CRT-D therapy according to clinical guidelines
* Planned for de novo implantation of a BIOTRONIK ICD or CRT-D in combination with Pamira
* Ability to understand the nature of the study and willingness to provide written informed consent
* Ability and willingness to perform all follow-up visits at the study site
* Ability and willingness to use the CardioMessenger and acceptance the BIOTRONIK Home Monitoring® concept

Exclusion Criteria

* Mechanical tricuspid valve prosthesis or a severe tricuspid valve disease
* Known Dexamethasone acetate intolerance
* Cardiac surgical post-implantation procedure planned within 12 months (including interventional procedures like ablation, valve replacement, heart transplant etc.)
* Less than 18 years old
* Pregnant or breast feeding
* Participating in another interventional clinical investigation
* Life-expectancy less than 12 months
Minimum Eligible Age

18 Years

Maximum Eligible Age

99 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Biotronik SE & Co. KG

INDUSTRY

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Thomas Deneke, Prof.

Role: PRINCIPAL_INVESTIGATOR

RHÖN-KLINIKUM Campus Bad Neustadt, Germany

Locations

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John Hunter Hospital

New Lambton Heights, New South Wales, Australia

Site Status

Medizinische Universität Graz

Graz, Styria, Austria

Site Status

UZ Brussels

Jette, , Belgium

Site Status

UZ Leuven Gasthuisberg

Leuven, , Belgium

Site Status

Universitätsklinikum Erlangen

Erlangen, Bavaria, Germany

Site Status

Klinikum der Universität München

München, Bavaria, Germany

Site Status

Universitätsklinikum Würzburg

Würzburg, Bavaria, Germany

Site Status

Immanuel Klinikum Bernau Herzzentrum Brandenburg

Bernau bei Berlin, Brandenburg, Germany

Site Status

St. Marienkrankhaus Klinikum Westmünsterland GmbH

Ahaus, North Rhine-Westphalia, Germany

Site Status

Städtisches Klinikum Dresden-Friedrichstadt

Dresden, Saxony, Germany

Site Status

Otto-von-Guericke-Universität Magdeburg

Magdeburg, Saxony-Anhalt, Germany

Site Status

Klinikum Dorothea Christiane Erxleben Quedlinburg

Quedlinburg, Saxony-Anhalt, Germany

Site Status

SRH Wald-Klinikum Gera GmbH

Gera, Thuringia, Germany

Site Status

SRH Zentralklinikum Suhl GmbH

Suhl, Thuringia, Germany

Site Status

Städtisches Klinikum Brandenburg GmbH

Brandenburg, , Germany

Site Status

State Hospital of Cardiology

Balatonfüred, , Hungary

Site Status

Semmelweis University

Budapest, , Hungary

Site Status

The University of Pécs

Pécs, , Hungary

Site Status

Assuta Medical Center

Ashdod, , Israel

Site Status

Soroka Medical Center

Beersheba, , Israel

Site Status

Shaare Zedek MC

Jerusalem, , Israel

Site Status

Pauls Stradins Clinical University Hospital

Riga, , Latvia

Site Status

Stredoslovenský ústav srdcových a cievnych chorôb, a.s. (SÚSCCH, a.s.)

Banská Bystrica, , Slovakia

Site Status

Countries

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Australia Austria Belgium Germany Hungary Israel Latvia Slovakia

Other Identifiers

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TA117

Identifier Type: -

Identifier Source: org_study_id

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