A Study to Evaluate Efficacy and Safety of Epoetin Beta (NeoRecormon®) in Anemic Participants With Breast Cancer Undergoing Chemotherapy

NCT ID: NCT02761642

Last Updated: 2018-08-24

Study Results

Results available

Outcome measurements, participant flow, baseline characteristics, and adverse events have been published for this study.

View full results

Basic Information

Get a concise snapshot of the trial, including recruitment status, study phase, enrollment targets, and key timeline milestones.

Recruitment Status

COMPLETED

Clinical Phase

PHASE2

Total Enrollment

200 participants

Study Classification

INTERVENTIONAL

Study Start Date

2004-02-29

Study Completion Date

2007-03-31

Brief Summary

Review the sponsor-provided synopsis that highlights what the study is about and why it is being conducted.

This study will evaluate the efficacy and safety of subcutaneous (SC) epoetin beta in anemic participants with breast cancer undergoing chemotherapy.

Detailed Description

Dive into the extended narrative that explains the scientific background, objectives, and procedures in greater depth.

Conditions

See the medical conditions and disease areas that this research is targeting or investigating.

Anemia

Study Design

Understand how the trial is structured, including allocation methods, masking strategies, primary purpose, and other design elements.

Allocation Method

NA

Intervention Model

SINGLE_GROUP

Primary Study Purpose

TREATMENT

Blinding Strategy

NONE

Study Groups

Review each arm or cohort in the study, along with the interventions and objectives associated with them.

Epoetin Beta

Anemic breast cancer participants will receive epoetin beta treatment for 12 weeks.

Group Type EXPERIMENTAL

Epoetin Beta

Intervention Type DRUG

All participants will receive epoetin beta at a dose of 30000 International Units (IU) as SC injection once every week for a total of 12 weeks. Adjustments in the dose will be implemented based on the participant's blood hemoglobin levels.

Interventions

Learn about the drugs, procedures, or behavioral strategies being tested and how they are applied within this trial.

Epoetin Beta

All participants will receive epoetin beta at a dose of 30000 International Units (IU) as SC injection once every week for a total of 12 weeks. Adjustments in the dose will be implemented based on the participant's blood hemoglobin levels.

Intervention Type DRUG

Other Intervention Names

Discover alternative or legacy names that may be used to describe the listed interventions across different sources.

NeoRecormon

Eligibility Criteria

Check the participation requirements, including inclusion and exclusion rules, age limits, and whether healthy volunteers are accepted.

Inclusion Criteria

* Adult female participants with histological diagnosis of breast cancer
* Any type of chemotherapy planned for greater than or equal to (\>/=) 9 weeks
* Hemoglobin level less than (\<) 11 grams per deciliter (g/dL)
* Participants able to receive iron supplement, if necessary

Exclusion Criteria

* Known or suspected contraindications to epoetin beta
* Pregnancy or lactation period
* Diagnosis of anemia only due to iron-deficiency
* Diagnosis of thalasemic syndromes
* Epilepsy and/or cerebral metastasis
* Blood transfusion or treatment with any erythropoietic factor within 4 weeks before study start
Minimum Eligible Age

18 Years

Eligible Sex

FEMALE

Accepts Healthy Volunteers

No

Sponsors

Meet the organizations funding or collaborating on the study and learn about their roles.

Hoffmann-La Roche

INDUSTRY

Sponsor Role lead

Responsible Party

Identify the individual or organization who holds primary responsibility for the study information submitted to regulators.

Responsibility Role SPONSOR

Principal Investigators

Learn about the lead researchers overseeing the trial and their institutional affiliations.

Clinical Trials

Role: STUDY_CHAIR

Hoffmann-La Roche

Locations

Explore where the study is taking place and check the recruitment status at each participating site.

Arezzo, , Italy

Site Status

Ascoli Piceno, , Italy

Site Status

Bussolengo VR, , Italy

Site Status

Busto Arsizio, , Italy

Site Status

Casale Monferrato, , Italy

Site Status

Catania, , Italy

Site Status

Catanzaro, , Italy

Site Status

Chieti, , Italy

Site Status

Cuneo, , Italy

Site Status

Fano, , Italy

Site Status

Florence, , Italy

Site Status

Frosinone, , Italy

Site Status

Genova, , Italy

Site Status

Macerata, , Italy

Site Status

Messina, , Italy

Site Status

Monza, , Italy

Site Status

Napoli, , Italy

Site Status

Nocera Inferiore, , Italy

Site Status

Pavia, , Italy

Site Status

Pisa, , Italy

Site Status

Pordenone, , Italy

Site Status

Roma, , Italy

Site Status

Roma, , Italy

Site Status

Sassari, , Italy

Site Status

Torino, , Italy

Site Status

Vecchiazzano, , Italy

Site Status

Vittorio Veneto, , Italy

Site Status

Countries

Review the countries where the study has at least one active or historical site.

Italy

Other Identifiers

Review additional registry numbers or institutional identifiers associated with this trial.

ML17503

Identifier Type: -

Identifier Source: org_study_id

More Related Trials

Additional clinical trials that may be relevant based on similarity analysis.

Chemotherapy Related Anemia
NCT00035607 COMPLETED PHASE2